ACTIGRAPHY AND POLYSOMNOGRAPHY IN ASTHMA

本研究旨在验证活动描记术可以检测与症状相关的夜间哮喘变化的假设。我们将证实最佳的药物治疗可以改善夜间哮喘患者的睡眠质量。然后，我们将尝试证明，活动描记术将检测由多导睡眠描记术记录的有夜间症状的哮喘患者的睡眠片段，以及通过优化医疗管理实现的睡眠改善。夜间哮喘患者将佩戴活动记录仪三个晚上，其中一个晚上将包括传统的多导睡眠仪。他们的药物将被优化，两周后，这个过程将被重复。肺功能检查将在入院时和两周后进行。数据将通过我们设计的一种称为连续历元频率分析（FACE）的独特分析方法进行分析。我们将把这些结果与多导睡眠图、哮喘问卷和睡眠问卷的结果进行比较。

This study seeks to test the hypothesis that actigraphy can detect changes in nocturnal asthma that correlate with symptoms. We will confirm that optimal medical therapy improves sleep quality in patients with nocturnal asthma. We will then attempt to demonstrate that actigraphy will detect the fragmented sleep documented by polysomnography in asthmatics with nocturnal symptoms and the improved sleep achieved by optimizing medical management. Patients with nocturnal asthma will wear the actigraph for three nights, one of which will include traditional polysomnography. Their medications will be optimized, and in two weeks the process will be repeated. Pulmonary function tests will be done at entry and at two weeks time. Data will be analyzed by a unique analytic measure called Frequency Analysis of Consecutive Epochs (FACE) that we have designed. We will compare these results with those from polysomnography, an asthma questionnaire and a sleep questionnaire.