Center for Computational Biology and Bioinformatics

我们建议建立一个计算生物学和生物信息学中心，作为哥伦比亚大学研究和教育的焦点。该中心将通过促进实验室和计算科学家之间的合作，通过培训计划、研讨会和研讨会，并通过提供该领域尖端研究所需的计算基础设施和支持，促进将计算方法整合到生物医学研究的不同领域。内部研究将包括DNA和蛋白质序列分析、SNP分析及其与人类疾病的关系、蛋白质结构分析、微阵列分析、完整 基因组，蛋白质的功能注释，相互作用蛋白质网络的研究，以及基于3D结构的新药设计。该中心将通过与参与部门开发联合课程和学位计划，在教育中发挥核心作用。还将建立一个工业推广计划，在该计划中，工业科学家将能够参加中心讲座、座谈会和研讨会，在中心度过迷你假期，并与中心科学家建立研究联系。

We propose to establish a Center for Computational Biology and Bioinformatics that will serve as a focal point for research and education at Columbia. The center will facilitate the integration of computational methods into different areas of biomedical research through the fostering of collaborations between laboratory and computational scientists, through training programs, workshops and seminars, and by providing the computational infrastructure and support that is necessary for cutting-edge research in this area. In-house research will include areas such as DNA and protein sequence analysis, SNP analysis and its relationship to human disease, protein structure analysis, the analysis of microarrays, the analysis and comparison of complete genomes, functional annotation of proteins, the study of networks of interacting proteins, and the 3D structure-based design of new pharmaceuticals. The center will play a central role in education through the development of joint courses and degree programs with participating departments. An industrial outreach program will also be established in which industrial scientists will be able to attend center lectures, symposia and workshops, spend mini-sabbaticals at the center, and establish research contacts with center scientists.