Intelligent Wireless Adaptive Reconfigurable EEG

描述(申请人提供)：本方案的具体目标是开发一种具有实时自适应和重新配置能力的移动无线脑电监测系统。总体目标是使动态监测更加稳健、准确、临床相关和实用。两大创新是：1-实时自适应能力，调整采集和传输的脑电数据的数量和质量，以更好地反映潜在的临床事件(如癫痫发作)；2-通过实时自动重新配置脑电采集系统，实现更实用和更准确的动态监测。 这项提议旨在通过赋予我们最先进的微型生物遥测技术动态、实时、自适应和重新配置的能力，将其提高到一个新的复杂水平。因此，我们将利用克利夫兰医疗设备公司无线医疗技术的灵活和软件可控的架构，并将开发创新的解决方案，极大地改善对脑电(和其他生物潜力)的动态和远程监测。总体目标(第一阶段、第二阶段和第二阶段)是开发一种智能脑电监测器，该监测器可以根据潜在的临床情况自动调整其数据采集参数，并优化可用带宽的使用。它还将能够实时动态地重新配置自己，以补偿严重的数据损坏事件，例如当一个或几个电极松动或分离时。 拟议的商业应用：拟议的系统旨在改进EEG的动态和远程监测，以诊断癫痫和非癫痫发作。该计划将开发的自适应和可重构的生物遥测技术将立即适用于其他生物潜力和生理系统的长期和动态监测，包括多导睡眠图和中风监测。

DESCRIPTION (provided by applicant): The specific aim of this proposal is to develop an ambulatory wireless EEG monitoring system with real-time adaptive and re-configuration capabilities. The overall goal is to make ambulatory monitoring more robust, accurate, clinically relevant, and practical. The two major innovations are: 1- Real-time adaptive capability for adjusting the quantity and quality of the acquired and transmitted EEG data to better reflect the underlying clinical event (such as a seizure), 2- more practical and accurate ambulatory monitoring by the real-time automatic reconfiguration of the EEG acquisition system. This proposal intends to take our state-of-the-art miniature bio-telemetry technology to the next level of sophistication by endowing it with dynamic real-time adaptive and reconfiguration capability. Thus, we will take advantage of the flexible and software-controllable architecture of the Cleveland Medical Devices Inc. wireless medical technology and will develop innovative solutions that will greatly improve ambulatory and remote monitoring of EEG (and other bio-potential). The overall goal (Phase I, II, and Ill) is to develop an Intelligent EEG monitor that can automatically adapt its data acquisition parameters to the underlying clinical situation and optimize the use of available bandwidth. It will also be able to dynamically reconfiguring itself in real-time to compensate for serious data-corrupting events such as when one or several electrodes become loose or detached. PROPOSED COMMERCIAL APPLICATION: The proposed system intends to improve the ambulatory and remote monitoring of EEG for diagnosis of epileptical and non-epileptical seizures. The adaptive and reconfigurable bio-telemetry technology that will be developed in this program will have immediate applicability to the long-term and ambulatory monitoring of other bio-potential and physiological systems including polysomnography and stroke monitoring.