LOCALIZED MEASUREMENTS OF HYPERPOLARIZED 3HE DIFFUSION & T2 IN GUINEA PIG LUNG

磁共振显微镜可能有助于理解当一个人的大脑出现异常时会发生什么。 异物被放置在体内，用于成像或 测量化学环境。 我们将图像，与植入 线圈，硅涂层上纤维囊的发展， 围绕成像线圈。 将在1、7、14和28时进行成像 植入后天数。 固定后，线圈和周围 组织将被取出并以更高的分辨率离体成像。 最后，纤维囊和线圈的复合体将通过 常规显微镜。

MR microscopy may contribute to understanding what happens when a foreign body is place in the body for purposes of either imaging or measuring the chemical environment. We will image, with implanted coils, the development of fibrous capsule on the silicone coating that surrounds the imaging coil. Imaging will be done at 1, 7, 14 and 28 days after implant. Following fixation, the coil and surrounding tissue will be removed and imaged ex vivo at higher resolution. Finally, the complex of fibrous capsule and coil will be imaged by conventional microscopy.