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Predoc Training at the Interface Chemistry and Biology

Predoc Training at the Interface Chemistry and Biology
化学与生物学界面的 Predoc 培训
批准号:
6592064
负责人:
CRAIG M CREWS
金额:
$16.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-07-01 至 2008-06-30

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中文摘要
翻译
描述(由申请人提供):本申请要求在耶鲁大学化学/生物学接口的新培训计划的资金。在过去的五年中,耶鲁大学有意识地努力通过在分子、细胞和发育生物学、化学、药理学和分子生物物理学和生物化学(MB&B)部门的初级和高级职位上的新招聘和晋升来增加其在这一领域的代表性。这种扩张大大提高了我们在这个极其重要的研究领域培养学生的能力。考虑到耶鲁大学在合成和机械化学以及分子生物学和生物化学方面的现有优势,这些新的任命创造了一个界面培训的环境,这与耶鲁大学几十年来所经历的任何事情都不同。耶鲁大学化学生物学项目涉及来自五个部门的25名培训师。 正在寻求为12名博士前受训人员提供支助。所有被录取的学员将至少拥有相关领域的学士学位。学员将通过申请进入化学系或非常成功的耶鲁生物和生物医学科学(BBS)计划中的新化学生物学轨道。无论进入模式,所有学员将分享一个共同的第一年的经验,涉及跨学科的课程工作,实验室轮换,以及密切监督和指导研究生主任与执行委员会一起。在第一年结束时,学员将从CBP培训师中选择一名论文顾问和共同导师,并在第二年开始密集的研究。所有学生至少教一年,以帮助他们作为教师学者的培训。增加少数民族受训人员的人数和提供与研究有关的伦理问题教育的方案是这一培训方案的重要组成部分。预计学员将需要5至6年的时间才能完成博士学位的培训。 培训计划的特点包括跨部门的课程工作,包括专门为新学员设计的课程,严格的跨部门轮换时间表,在此期间,学员将在耶鲁大学的三个实验室体验科学,秋季化学生物学计划务虚会,每月内部研讨会计划,讨论最近的结果和年度化学生物学研讨会。
英文摘要
DESCRIPTION (provided by applicant): This application requests funds for a new training program at the Chemistry/Biology Interface at Yale University. Over the past five years Yale has made a conscious effort to increase its representation in this area through new hires and promotions at the junior and senior levels in the departments of Molecular, Cellular and Developmental Biology, Chemistry, Pharmacology and Molecular Biophysics and Biochemistry (MB&B). This expansion has dramatically enhanced our ability to train students in this exceedingly important research area. Taken with the current strengths in synthetic and mechanistic chemistry and in molecular biology and biochemistry for which Yale is distinguished, these new appointments create an environment for interfacial training that is unlike anything Yale has experienced in decades. The Yale Chemical Biology Program involves 25 trainers from five departments. Support is sought for 12 pre-doctoral trainees. All trainees admitted to the program will have at least a Bachelor's degree in a relevant field. Trainees will enter via an application to the chemistry department or to a new chemical biology track within the very successful Yale Biological and Biomedical Sciences (BBS) program. Regardless of mode of entry all trainees will share a common first year experience involving interdisciplinary course work, laboratory rotations, as well as close supervision and guidance from the director of graduate students in conjunction with the executive committee. At the end of their first year, trainees will chose a thesis advisor and co-mentor from among the CBP trainers and begin intensive research with additional courses in their second year. All students teach for at least one year to aid in their training as teacher-scholars. Programs for increasing the number of minority trainees and for providing education in ethical issues related to research represent important parts of this training program. It is expected that trainees will require 5 to 6 years to complete their training toward the Ph.D. Special features of the training program include interdepartmental course work, including specially designed courses for the new trainees, a rigorous interdepartmental rotation schedule during which the trainee will experience science in three laboratories at Yale, a Fall Chemical Biology Program Retreat, a monthly in-house seminar program for discussion of recent results and an annual Chemical Biology Symposium.
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Developing Tumor-specific PROTACs
  • 批准号:
    10244943
  • 项目类别:
  • 资助金额:
    $38.22万
  • 财政年份:
    2019
  • 负责人:
    CRAIG M CREWS
  • 依托单位:
Developing Tumor-specific PROTACs
  • 批准号:
    10470405
  • 项目类别:
  • 资助金额:
    $37.44万
  • 财政年份:
    2019
  • 负责人:
    CRAIG M CREWS
  • 依托单位:
Inducing Proximity: An Emerging Paradigm for New Therapeutic Modalities
  • 批准号:
    10518541
  • 项目类别:
  • 资助金额:
    $89.31万
  • 财政年份:
    2015
  • 负责人:
    CRAIG M CREWS
  • 依托单位:
Inducing Protein Degradation: A New Pharmaceutical Paradigm
  • 批准号:
    9142301
  • 项目类别:
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  • 财政年份:
    2015
  • 负责人:
    CRAIG M CREWS
  • 依托单位:
海外基金