AIDS RELATED RESEARCH CAGING

描述(由申请人提供)： ONPRC建议购买适合饲养SPF雄性印度裔恒河猴(Macaca Mulatta)的笼子，用于艾滋病相关研究。在ONPRC和全国范围内，对SPF猕猴用于艾滋病相关研究的需求不断增加，已经超过了扩大生产群体以供应更多动物的供应努力，因此有必要保留雌性后代用于繁殖，使得SPF雄性猕猴成为艾滋病相关研究项目的主要模型。ONPRC的动物生物安全2级和3级(ABLS2和ABSL3)隔离设施容纳了用于艾滋病相关研究的动物，但没有配备适合第四组雄性猕猴的笼子。现有的笼子没有6.0平方英尺。英国《金融时报》美国农业部要求的建筑面积，并且没有提供社会住房的选择。非常重要的是，用于艾滋病相关研究的动物有机会体验丰富的社会环境。本申请中要求的面积为6.2平方英尺。英国《金融时报》笼子和相关设备将符合美国农业部对第4组雄性猕猴的要求，并为艾滋病相关研究中使用的NHP提供广泛的环境浓缩和社会住房选择。

DESCRIPTION (provided by applicant): The ONPRC proposes to purchase caging suitable for housing SPF male Indian-origin rhesus macaques (Macaca mulatta) used in AIDS related research. Increasing demands for SPF rhesus macaques for AIDS related research at the ONPRC and nationally has exceeded the supply efforts to expand production colonies to supply more animals has necessitated retention of female offspring for breeding, leaving male SPF rhesus macaques as the primary model for AIDS-related research projects. The Animal Biosafety Level 2 and 3 (ABLS2 and ABSL3) containment facility which houses animals for AIDS-related research at the ONPRC is not equipped with cages suitable for Group 4 male rhesus macaques. The existing cages do not have the 6.0 sq. ft. of floor space required by USDA and do not provide the option of social housing. It is very important that animals used in AIDS-related research have the opportunity to experience an enriched social environment. Requested in this application are 6.2 sq. ft. cages and associated equipment that will comply with USDA requirements for Group 4 male rhesus macaques and provide a wide range of options for environmental enrichment and social housing of NHPs used in AIDS-related research.