CORE--CELL ANALYSIS

描述：(申请者描述)细胞分析核心设计用于 通过集中公共资源为临床和基础项目提供支持 程序。这些包括样品的获取、表征、分配 和储存，细胞分类，分析流式细胞术，组织学和 免疫组织化学和荧光原位杂交(FISH)。通过 集中采集样本，我们将能够保持记录 使用的每个样本的预期数据，从而提高了数据的效率 收集。将建立样本分发的优先列表，并 定期更新以适应不同项目的要求 细胞数量、样本类型、患者特征等术语 相关标准。这一机制将极大地提高工作效率。 不同项目的样本利用率。一种集中的组织学， 免疫组织化学和FISH服务将避免建立 在每个调查员S实验室的程序中，规定了一致性 程序和材料的有效利用。流式细胞术与细胞 所提供的分选服务将提供最先进的流式细胞仪和细胞 对此计划应用程序中的项目进行分类支持。不同的 核心的职能将由有足够能力的人来监督 在各种程序方面经验丰富。

DESCRIPTION: (Applicant's Description) The Cell Analysis Core is designed to provide support to the clinical and basic projects by centralizing common procedures. These include sample acquisition, characterization, distribution and storage, cell sorting, analytical flow cytometry, histology and immunohistochemistry, and fluorescence in situ hybridization (FISH). By centralizing sample acquisition, we will be able to maintain records of expected data for each sample used, thus, increasing the efficiency of data collection. A priority list for sample distribution will be established and updated periodically to accommodate requirements of the different projects in terms of cell numbers, sample type, patient characteristics, and other relevant criteria. This mechanism will greatly enhance the efficiency of sample utilization by the different projects. A centralized histology, immunohistochemistry, and FISH service will avoid the need to establish the procedures in each investigator?s laboratory, providing for uniformity of procedures and efficient use of materials. The flow cytometry and cell sorting service offered will provide state-of-the-art flow cytometry and cell sorting support to the projects in this program application. The different functions of the core will be supervised by able individuals with ample experienced in the various procedures.