CORE--BIOINFORMATICS

描述：（申请人描述）生物信息学的目的 设施是提供一个多学科的专业人员熟练的团队， 信息系统和物理科学领域，包括 微生物学和遗传学，谁能够把这些知识承担， 促进由同行评审，资助的研究人员进行的研究， FCCC. 1998 - 1999年生物信息学基金通过开发专门的 数据资源和/或计算机程序或程序系统 与受资助的研究人员的研究有关。该设施还使 共享软件工具和共享数据资源，供研究人员使用， 包括序列分析中的传统工具和数据集， 结构预测、蛋白质结构、成像、数学和统计学。 该设施提供咨询和个性化的培训， 这些工具和数据资源。提供先进的支持， 集成Internet、Web和关系数据库技术， 生物科学中的问题，如基因图谱，微阵列 分析、图像分析和数据采集。设施工作人员具有专业知识 在信息学和生物科学数据库利用方面， 软件设计方法、面向对象编程和成像。两 设施工作人员参加了生物信息学小组（单独） 基因组中心设施工作人员都是各种能力的程序员， 最新的语言和技术，包括Java，JavaScript，Internet 网络编程、HTML/XML、C/C++、Perl、Tcl/Tk和Python。 所有13个项目中的50名受资助的调查人员使用该设施及其 资源，并与14个受资助的 9个项目的研究人员。

Description: (Applicant's Description) The purpose of the Bioinformatics Facility is to provide a multidisciplinary team of professionals skilled both in information systems and areas of the physical sciences, including microbiology and genetics, who are able to bring this knowledge to bear to facilitate the research conducted by peer reviewed, funded investigators at FCCC. The Bioinformatics Facility provides support by developing specialized data resources and/or computer programs or systems of programs directly related to the research of funded investigators. The facility also makes shared software tools and shared data resources available for researchers, including traditional tools and datasets in sequence analysis, secondary structure prediction, protein structure, imaging, mathematics, and statistics. The facility provides consultation and individualized training in the use of these tools and data resources. Advanced support is provided for the use and integration of Internet, Web, and relational database technologies, to problems in the biological sciences, such as genetic mapping, micro-array analysis, image analysis, and data acquisition. Facility staff have expertise in informatics and bioscience database utilization, formal and structured software design methods, object oriented programming and imaging. Two of the facility staff have participated in the bioinformatics groups of (separate) genome centers. Facility staff are all capable programmers in a variety of the latest languages and techniques, including Java, Javascript, Internet network programming, HTML/XML, C/C++, Perl, Tcl/Tk, and Python. Fifty funded investigators in all 13 programs use the facility and its resources, and it has active, ongoing collaborations with 14 funded investigators in 9 programs.