Korean Acupuncture In Central Nervous System Disorders

描述(申请人提供)：韩国针灸在韩国被有效地用于治疗各种神经疾病，包括帕金森氏症、中风、疼痛和膀胱功能障碍。在美国，这种治疗模式的成功记录较少，尤其是在急性和康复中风环境中以及帕金森的S。对这种差异的可能解释包括：患者选择的标准；技术；特定的结果衡量标准；患者的信念；报告的方法和其他未知因素。这笔NIH计划拨款支持韩国庆熙大学和北卡罗来纳州大学教堂山分校的研究人员开展合作研究，研究两种文化中的韩国针灸，以此来了解作用机制和在应用于特定神经疾病时优化结果的因素。该提案将汇集这两个机构在这些领域具有专业知识的调查人员，以开发想法和试点项目，从而产生更广泛的研究提案。该提案要求为发展并行、互动的行政结构提供资金，以支持探索创新的研究战略、项目开发和调查员培训。这笔赠款将为有效合作开发必要的基础设施提供资金，这些基础设施将导致竞争性提案，整合人类疾病的动物模型、临床试验以及韩国针灸和神经疾病的翻译研究。

DESCRIPTION (provided by applicant): Korean acupuncture is used effectively for a variety of neurological conditions in Korea, including Parkinson's disease, stroke, pain, and bladder dysfunction. Success with this mode of therapy in the United States is documented less consistently, particularly in acute and rehabilitative stroke settings and Parkinson' s. Possible explanations for this disparity include variations in: criteria for patient selection; technique; specific outcome measures; patient beliefs; methods of reporting and other unknown factors. This NIH planning grant supports development of collaborative research efforts between investigators at Kyung Hee University in Korea and UNC - Chapel Hill for the study of Korean acupuncture in the two cultures as a way of understanding mechanisms of action and factors that optimize outcomes when applied to specific neurological conditions. The proposal will bring together investigators from the two institutions with expertise in these areas to develop ideas and pilot projects leading to more extensive research proposals. The proposal requests funding for development of parallel, interactive administrative structures to support exploration of innovative research strategies, project development and investigator training. The grant will provide funding for the development of the necessary infrastructure for effective collaboration that will lead to competitive proposals integrating animal models of human disease, clinical trials, and translational research in Korean acupuncture and neurological disorders.