ADOLESCENT TRIAL NETWORK FOR HIV/AIDS BALTIMORE

描述：(申请人提供)：马里兰大学星轨 青少年艾滋病计划(STAR Track Program)是一个临床和研究单位 在青少年艾滋病毒研究领域拥有丰富的经验。星星 Track是马里兰州唯一的青少年专属艾滋病毒服务机构 并拥有全面的“一站式购物”模式，全州范围内 社区外展计划，这是一个通过 青少年专门的艾滋病毒咨询和检测单位，以及青年关爱网络 这是艾滋病毒携带者和艾滋病毒感染者的转介网络。我们的节目有 自1994年以来一直是青少年艾滋病毒/艾滋病研究网络的15个站点之一 在招聘、留住员工、现场绩效、 质量保证。我们的PI、研究协调员和青年社区咨询 董事会成员卓有成效地参与并为 AMHARN的使命和目标。我们的项目在以下方面有丰富的经验 在临床护理中招募和保留艾滋病毒阳性青少年和艾滋病毒感染青少年 研究，以及105名艾滋病毒+青年(其中许多人有 研究经验)和125名艾滋病毒青年。星际赛道有很强的临床和 与其他临床站点合作研究总共180例艾滋病毒 感染了24岁以下的年轻人。我们的节目非常有经验 青少年研究人员和研究协调员以及基础和临床 儿科免疫学部和人类研究所的研究人员 马里兰大学的病毒学。这些调查人员有广泛的 在多中心协作试验中的领导力记录。紧绷的 社区外展、艾滋病毒早期识别、与 护理和研究，以及全面的初级和次级专科护理，内在 以明星赛道？S架构，助力ATN大目标。这些 人际关系也为扩大学科招聘提供了一个很好的结构。 本申请详细说明了该公司目前的临床和研究能力 青少年医学试验股(AMTU)进行与以下方面相关的研究方案 艾滋病毒的一级、二级和三级预防。高危人群 可用于这项研究的对象包括高危性少数群体和异性恋 青少年，以及被监禁和滥用物质的青少年。此外，它还 包括处于过渡性住房状况的青年和辍学的青年。 此外，与经验丰富的实验室、数据库的强大合作 经理和马里兰大学其他在艾滋病毒方面有专长的科学家 临床试验和疫苗开发为 丰富ATN的基础科学和以实验室为基础的议程。

DESCRIPTION: (provided by applicant): The University of Maryland STAR TRACK Adolescent HIV Program (STAR TRACK Program) is a clinical and research unit with significant experience in the areas of adolescent HIV research. STAR TRACK is the only adolescent exclusive HIV service in the state of Maryland and has a comprehensive "one stop shopping" model of care, a state wide community outreach program, an HIV early identification program through an adolescent specific HIV counseling and testing unit, and a Youth Care Network that serves as referral network for both HIV+ and HIV-youths. Our program has been one of 15 sites of the Adolescent HIV/AIDS Research Network since 1994 with a successful track record of recruitment, retention, site performance, quality assurance. Our PI, study coordinators, and Youth Community Advisory Board member have productively participated in and contributed towards the AMHARN mission and its goals. Our program has extensive experience in the recruitment and retention of HIV+ and HIV-adolescents in clinical care and research, and an active caseload of 105 HIV+ youths (many of whom have research experience) and 125 HIV-youths. STAR TRACK has strong clinical and research collaborations with other clinical sites for a total of 180 HIV infected young people under the age of 24. Our program has highly experienced adolescent researchers and study coordinators as well as basic and clinical researchers of the Division of Pediatric Immunology and the Institute of Human Virology of the University of Maryland. These investigators have an extensive track record of leadership in multicenter collaborative trials. The tight interface between community outreach, early identification of HIV, linkage to care and research, and comprehensive primary and subspecialty care, intrinsic to STAR TRACK?s structure, facilitates the major goals of the ATN. These relationships also provide a great structure to expand subject recruitment. This application details the current clinical and research capacity of the Adolescent Medicine Trial Unit (AMTU) to conduct research protocols related to the primary, secondary and tertiary prevention of HIV. High-risk populations available for this research include high-risk sexual minority and heterosexual youths, as well as incarcerated and substance abusing youths. In addition, it includes youths in transitional housing situation and school dropouts. Furthermore, the strong collaboration with an experienced laboratory, database manager and other University of Maryland scientists with expertise in HIV clinical trials and vaccine development provides an optimal environment for enriching the basic science and laboratory-based agenda of the ATN.