Training in Aging Research

描述（由申请人提供）：T32机构国家研究服务奖的新申请以老龄化研究中强大且不断增长的研究项目为中心，包括一组精选的导师，他们在老龄化相关研究中有着资金充足的科学努力。这些研究人员为爱因斯坦新一代老龄化研究人员的招募和培训提供了良好的基础。目前的新申请建立在1989年9月阿尔伯特爱因斯坦医学院（AECOM）首次授予的早期T32资助的基础上，并于1994年进行了竞争性更新。我们已经选择包括一个“两年的建设”期，旨在重新在爱因斯坦这个程序，提高其知名度在我们的机构内外，并实施新的招聘策略。在这方面，我们计划初期共招收五名学员，并在申请的第三年开始，将学员总数由五名增至七名。另一方面，还应该指出的是，自1999年以来，该机构加强了对老龄化研究的承诺，部分反映在国家老龄化研究所（NIA），其他相关的NIH研究所，美国老龄化研究联合会（AFAR）和埃里森基金会增加了研究资金。在这方面，在此期间，NIA资助的爱因斯坦研究人员数量从6人增加到14人，而这些奖项的年度直接成本增加了一倍多，达到约500万美元。最近老龄化研究的快速增长为爱因斯坦的老龄化研究培训提供了新的机会。 本申请中代表的研究学科包括衰老的代谢综合征;衰老脑功能和神经退行性疾病;心血管和衰老细胞功能;免疫学和衰老;生长因子，细胞信号传导和癌症;以及衰老，更年期和女性健康。我们的研究互动和博士前和博士后学员在生物学原则的联合培训，使自己成为一个高度整合和有凝聚力的计划。通过正式的课程工作，参加研究研讨会和个人研究项目，学员可以发展必要的技能，在老龄化研究的独立职业。

DESCRIPTION (provided by applicant): This new application for a T32 Institutional National Research Service Award is centered on strong and growing research programs in aging research and includes a selective group of mentors with well-funded scientific endeavors in aging-related research. These investigators provide an outstanding foundation for the recruitment and training of a new generation of aging researchers at Einstein. The current new application builds on the foundation of an earlier T32 grant first awarded at the Albert Einstein College of Medicine (AECOM) in September 1989, and competitively renewed in 1994. We have elected to include a "two-year build-up" period designed to reinstitute this program at Einstein, promote its visibility within and outside our Institution, and implement novel recruitment strategies. In this regard, we plan to initially enroll a total of five trainees and to increase the total number of trainees from five to seven starting on the third year of this application. On the other hand, it should also be noted that since 1999, this Institution has enhanced its commitment to aging research as partly reflected by increasing research funding from the National Institute of Aging (NIA), other relevant NIH Institutes, the American Federation for Aging Research (AFAR), and the Ellison Foundation. In this regard, the number of Einstein investigators funded by the NIA rose from 6 to 14 during this period of time, while the annual direct cost of these awards more than doubled to approximately 5 million dollars. The recent rapid growth in aging research provides renewed opportunities for training in aging research at Einstein. The research disciplines represented in this application include metabolic syndromes of aging; aging brain functions and neurodegenerative diseases; cardiovascular and aging cellular functions; immunology and aging; growth factors, cell signaling, and cancer; and aging, menopause and women's health. Our research interactions and the joint training of pre-doctoral and post-doctoral trainees in principles of biogerontology lend themselves to a highly integrated and cohesive program. Through formal course work, participation in research seminars, and individual research projects, trainees can develop the skills necessary for independent careers in aging research.