Training in the Molecular Biology of Neurodegeneration

描述(由申请人提供)：我们建议继续一项高度 成功的跨部门和跨机构培训计划 神经退行性变的分子生物学-致力于培训 独立研究科学家职业生涯的博士后和博士后 在大学和与健康相关的研究实验室。训练员们都是 哈佛大学教职员工积极研究阿尔茨海默氏症和 其他与衰老有关的神经退行性疾病。它们是从 哈佛医学院和五家附属研究医院：贝丝 以色列--女执事医院、布里格姆妇女医院、儿童医院、 马萨诸塞州综合医院和麦克莱恩医院。带来了广泛的 关于年龄相关问题的经验和实验方法 神经变性，该计划的教职员工包括分子生物学家， 遗传学家、细胞生物学家、神经病理学家和生物化学家。 博士前学生被录取到研究生中，并从研究生中抽取 哈佛医学院神经科学学位授予项目的学生 学校。博士后学生是从提名的申请者中挑选出来的。 由本项目的个别教员提供。共有六名博士后 实习生和8名博士后实习生拟进行初级培训 由31名在基础和应用研究方面经验丰富的教师组成 年龄相关性神经退行性变。在所有情况下，成功的主要标准是 应聘者对衰老和神经退行性疾病的研究有奉献精神和兴趣 并在之前的培训中取得了最高水平的学业成绩。全 学生被要求参加特殊的神经退行性变课程和 研讨会。该计划的目的是建立一个框架，在这个框架内 对致力于老龄化问题的未来研究人员的最佳培训 神经退行性变可以发生，已经广泛的相互作用 该计划的教员可以继续。

DESCRIPTION (provided by applicant): We propose to continue a highly successful inter-departmental and inter-institutional Training Program in the Molecular Biology of Neurodegeneration - a program devoted to the training of pre- and postdoctoral students for careers as independent research scientists in universities and health-related research laboratories. The trainers are all Harvard faculty with active research programs in Alzheimer's disease and other neurodegenerative disorders related to aging. They are drawn from the Harvard Medical School and five affiliated research hospitals: Beth Israel-Deaconess Hospital, Brigham and Women's Hospital, Children's Hospital, Massachusetts General Hospital, and McLean Hospital. Bringing a wide range of experience and experimental approaches to the problems of age-related neurodegeneration, the Program faculty include molecular biologists, geneticists, cell biologists, neuropathologists, and biochemists. The pre-doctoral students are recruited into and drawn from the graduate students in the degree-granting Neuroscience Program of the Harvard Medical School. The postdoctoral students are chosen from among applicants nominated by individual faculty members of the Program. A total of six pre-doctoral trainees and eight postdoctoral trainees is proposed for a primary training faculty of 31 individuals experienced in basic and applied studies of age-related neurodegeneration. In all cases, the main criteria for successful candidates is dedication and interest in aging and neurodegeneration research and the highest level of academic achievement in their previous training. All students are required to participate in special neurodegeneration courses and seminars. The purpose of the Program is to create a framework within which the best training of future researchers devoted to problems in aging and neurodegeneration can take place and the already extensive interactions among the Program faculty can be continued.