Molecular Biology Across Scales Training Program

跨尺度分子生物学培训计划

• 批准号: 10555915
• 负责人: David Bilder
• 金额: $ 180.56万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10555915
• 关键词: Molecular Biology; Training Programs

Project Summary / Abstract Molecular Biology Across Scales (MBAS) is a new multidisciplinary predoctoral training program that will develop the next generation of researchers discovering how molecules, cells, and tissues interact to create life and how this information can advance human health. MBAS will be the only graduate program at the University of California, Berkeley that supports broad-based training in multiple disciplines of molecular biology, rather than specialization within a particular discipline. This perspective has driven many of the transformative biological discoveries of recent years, including several made by MBAS faculty. MBAS will draw its students and faculty from the Department of Molecular & Cell Biology (MCB) Graduate Program, uniting those who tackle fundamental research problems at length scales ranging from individual molecules to complex biochemical systems to whole organisms. It will appoint 40 students (20 first-year trainees annually for a two-year term) with a target of 30% from historically excluded groups in the biological sciences. MBAS will provide diverse training opportunities for its diverse student body, encouraging each trainee to explore a wide range of research fields in their early years and identify those that most fully engage their individual passion. MBAS students will be required to publish a first-author paper and graduate with a mean time to degree of 5.5 years. The curriculum will impart broad conceptual knowledge, creative and critical thinking, mastery of experimental logic and methods, application of computational and quantitative approaches, rigorous analysis and interpretation of results, clear and fluent communication of findings, and incorporation of responsible, safe, and ethical practices. Students will choose formally-trained mentors from a faculty of 75 nationally recognized leaders who represent a wide choice of research areas and technical approaches, use state-of-the-art facilities, and work in an interactive, diverse and collaborative environment. MBAS will provide training, oversight, and support for its participating faculty, and will carefully monitor the progress of its trainees. Students will be well-supported with inclusive learning communities, rigorous and clear expectations, expert advising, and a program design that accounts for differences in preparation. Innovative training elements include new courses and enhanced content in responsible conduct of research and reproducibility, quantitative biology and data science, lab safety, and scientific writing. To further strengthen recruitment and retention, MBAS will mount initiatives to bolster diversity, equity, inclusion, and belonging. New programs will be piloted and evaluated with the goal of scaling the most successful of them to benefit all trainees within MCB. Professional skills development, experiential learning opportunities, and career counseling will prepare trainees for research-related careers of their choosing in academia, industry, government, non-governmental organizations, and beyond. In sum, MBAS will provide an early and persistent emphasis on multidisciplinary training, centered around the student experience, for a flexible and individually directed path to a successful career in the biomedical workforce.

项目总结/摘要 跨尺度分子生物学（MBAS）是一个新的多学科博士前培训计划，将 培养下一代研究人员，发现分子、细胞和组织如何相互作用创造生命 以及这些信息如何促进人类健康。MBA将是该大学唯一的研究生课程 支持分子生物学多学科的广泛培训，而不是 在特定的学科中进行专业化。这种观点推动了许多变革性的生物学 近年来的发现，包括MBAS教师的几个。MBA将吸引学生和教职员工 来自分子与细胞生物学系（MCB）研究生课程，团结那些谁解决 从单个分子到复杂的生物化学物质， 系统到整个生物体。它将任命40名学生（每年20名一年级学员，任期两年）， 目标是30%来自生物科学领域历史上被排斥的群体。MBAS将提供多样化的培训 机会，其多样化的学生团体，鼓励每个学员探索广泛的研究领域， 他们的早年，并确定那些最充分地发挥他们的个人激情。MBA学生必须 发表第一作者论文并毕业的平均时间为5.5年。课程将传授 广泛的概念知识，创造性和批判性思维，掌握实验逻辑和方法， 应用计算和定量方法，严格分析和解释结果，明确 和流畅的沟通结果，并纳入负责任，安全和道德的做法。学生将 从75名国家认可的领导人中选择经过正式培训的导师，他们代表了广泛的选择 的研究领域和技术方法，使用国家的最先进的设施，并在一个互动的，多样化的工作 合作的环境。MBAS将为其参与的教师提供培训，监督和支持， 会密切监察学员的进度。学生将得到良好的支持与包容性学习 社区，严格和明确的期望，专家咨询，以及一个计划设计，占 准备的差异。创新的培训内容包括新的课程和增强的内容， 负责任地进行研究和再现性，定量生物学和数据科学，实验室安全，以及 科学写作。为了进一步加强招聘和保留，MBAS将采取措施，以加强多样性， 公平、包容和归属。新的计划将进行试点和评估，目标是扩大最大的 这些培训的成功将使MCB内的所有学员受益。专业技能发展，体验式学习 机会，职业咨询将为学员选择与研究相关的职业做好准备， 学术界、工业界、政府、非政府组织等。总之，MBAS将提供一个 早期和持续强调多学科培训，围绕学生的经验，为一个灵活的 和个人指导的道路，以成功的职业生涯中的生物医学劳动力。