Training in Drug Abuse and Brain Imaging

描述：（申请人提供）： 这是一个建议，建立一个博士后研究培训计划， 人类大脑成像和药物滥用领域。当大脑的十年到来时， 两年前，我们有了更精致的大脑， 成像工具。需要这样一个专门的计划是由 人类麸皮成像领域的爆炸性增长， 新的和创新的技术的出现，以查看解剖和 在各种条件下大脑的功能方面， 物质滥用，如急性中毒的影响，跟踪线索诱导 渴望，测量认知效果，检测持续的神经和 认知缺陷，监测戒断，睡眠障碍，药物治疗 依从性，跟踪治疗进展和药物开发。因为 涉及人脑成像的子学科的性质和范围是 如此复杂，一批新的具有脑科学背景的临床科学家 成像技术，神经科学，药理学，成瘾医学和 治疗将需要整合大脑成像领域与 探索药物滥用的神经生物学基础，从而填补了 在美国和国外的研究中心的预期空缺-这 T32研究培训计划旨在填补这一空白。我们建议 建立一个综合的、多学科的药物滥用和脑成像 培训计划（DABITP）将由姆克林联合支持 医院/哈佛医学院和波士顿大学医学院。的 这些计划的成功主要取决于许多人的高素质。 有才华的教师和目前的学员群体。连同 思想和学生的重要交叉培养环境以及 积极和富有成效的合作的良好记录， 我们已经做好了奋进。3年博士后计划 培训计划的结构将为学员提供 脑磁共振和电生理测量基础 活动（第一年），然后在三个不同的设计之一放置 研究轨道，满足学员未来的职业目标：1）MR技术 和仪器轨道; 2）基础临床研究轨道;和3）临床 治疗跟踪。脑成像教学培训与 精神药理学在各种高度 成功的研究实验室将为我们提供下一代的 药物滥用研究人员谁配备采用脑成像技术， 他们开始了下一个十年对成瘾大脑的研究。

DESCRIPTION: (Provided by Applicant): This is a proposal to establish a postdoctoral research training program in the field of human brain imaging and drug abuse. As the Decade of the Brain came to a close two years ago, we have at our disposal a more refined variety of brain imaging tools. The need for such a dedicated program is dictated by the explosive growth of the field of human bran imaging that has led to an emergence of new and innovative techniques to view both the anatomical and functional aspects of the brain under a variety of conditions related to substance abuse such as acute intoxicating effects, tracking cue-induced craving, measuring cognitive effects, detecting persistent neurological and cognitive defects, monitoring withdrawal, sleep disturbances, medication compliance, tracking treatment progress and medication development. Because the nature and spectrum of the sub-disciplines involved in human brain imaging are so complex, a new breed of clinical scientists with backgrounds in brain imaging technology, neuroscience, pharmacology, addiction medicine and treatment will be needed to integrate the fields of brain imaging with the exploration of the neurobiological bases of drug abuse and thus fill the anticipated vacancies in research centers in the United States and abroad--this T32 Research Training Program is designed to fill this void. We propose to establish an integrated, multidisciplinary Drug Abuse and Brain Imaging Training Program (DABITP) to be jointly supported by the McLean Hospital/Harvard Medical School and Boston University School of Medicine. The success of these programs is based largely on the high caliber of the many talented faculty members and current group of trainees. Together with an environment of significant cross fostering of ideas and students as well as a proven record of active and productive collaboration, the foundation for such an endeavor is already well in place. The proposed three year post doctoral training program will be structured to provide the trainees with the fundamentals of magnetic resonance and electrophysiological measures of brain activity (year 1), followed by placement in one of three distinctly designed research tracks that meets the trainees future career goals: 1) MR Technology and Instrumentation Track; 2) Basic Clinical Research Track; and 3) Clinical Treatment Track. The combination of didactic training in brain imaging and psychopharmacology with practical applications in a variety of highly successful research laboratories will provide us with the next generation of drug abuse researchers who are equipped to employ brain imaging techniques as they embark on the next decade of research on the addicted brain.