TRANSLATIONAL RESEARCH AND SCIENCE EDUCATION

描述（由申请人提供）：IARC竞争更新申请的这一部分使IARC有资格获得潜在的指定和资助作为一个综合中心（P60）。该组成部分的总体目标是推进酒精研究及其传播，以改善对酗酒者的治疗和预防与酒精有关的问题。这将通过以下方式实现：(a)与其他机构，特别是少数民族和为少数民族服务的机构建立合作研究伙伴关系；(b)赞助和组织两年一次的博士前、博士后研究员和青年研究人员科学会议；(c)向临床环境中的治疗专业人员和整个社区，特别是州政府司法、行政和立法部门的专业人员提供继续教育的机会；(d)诊断和治疗酒精和药物滥用及依赖的临床教学（第三年）

DESCRIPTION (provided by applicant): This component of the IARC competing renewal application qualifies the IARC for potential designation and funding as a Comprehensive Center (P60). The overall objective of the component is to advance alcohol research and its dissemination for the purpose of improving the treatment of alcohol-affected individuals and the prevention of alcohol-related problems. This will be accomplished through: (a) collaborative research partnerships with other institutions, especially minority and minority-serving institutions; (b) sponsoring and organizing the biennial scientific conference for pre- and post-doctoral fellows and young investigators; (c) continuing education opportunities to treatment professionals in clinical settings and to the community at large, especially those in the judiciary, administrative and legislative branches of State government; (d) the clinical teaching of the diagnosis and treatment of alcohol and drug abuse and dependence for (3rd year) medical students, and extension of the educational base to masters degree level students in the IU School of Social Work; (e) the Bench to Bench Program of Science Education in Alcohol Problems for Indiana Judges. These activities will draw upon the expertise of the IARC-affiliated faculty at Indiana and Purdue Universities that reflect the broadly-based research theme of the center's research programs: a) The genetic determinants of alcohol ingestive behavior and other responses to alcohol, b) The interplay of genetic, behavioral and social risk factors in the etiology of alcoholism, c) The neurobiological basis of alcohol addiction as manifested by craving, loss of control drinking, and relapse, which will serve as the basis for rational pharmacotherapeutic interventions, d) The intimate interaction of the pharmacokinetics of alcohol with its pharmacodynamic actions and how individual variability in both these domains influence susceptibility to problem and dependent drinking.