Third Intl Symposium on Computational Cell Biology

描述（由申请人提供）：本基金旨在资助于2005年3月19日至23日在马萨诸塞州Lenox的Cranwell度假村和高尔夫俱乐部举行的“第三届计算细胞生物学国际研讨会”。计算细胞生物学是一个新兴的跨学科领域，它响应了对计算方法的需求，以分析和组织关于细胞结构和功能的大量复杂实验数据。虽然计算生物学的其他会议关注生物信息学和结构生物学，但这是唯一一个专门针对细胞生物学中计算建模应用的会议，主要针对细胞生物学家。该研讨会由位于康涅狄格大学健康中心生物医学成像技术中心的国家细胞分析和建模资源（NRCAM）组织。组委会由博士组成。Leslie M. Loew， NRCAM和CBIT主任，John Carson， NRCAM联合主任，Ann Cowan， CBIT副主任，NRCAM传播和培训主管，委员会主席。在2001年和2003年举行的前两次专题讨论会为细胞生物学家与理论家和计算机科学家提供了一个互动的场所，在他们的科学内容上取得了巨大成功，在不同科学家群体之间启动了新的交流水平，并定义了计算细胞生物学的新兴领域。本次研讨会的继续将有助于巩固和扩展计算细胞生物学家的社区，并继续弥合理论和实验细胞生物学家之间的学科差距。会议的科学焦点是目前正在开发建模方法的细胞生物学领域，或者已经成熟的计算建模方法。会议的主题将涵盖一系列细胞机制，包括细胞骨架和分子马达的调节、膜和蛋白质的运输、钙动力学的调节、信号转导途径和细胞周期控制。在这些领域中，使用高度定量实验方法和/或应用数学建模方法的研究人员将被邀请发言。会议形式是平台会议、海报会议、小型研讨会和教程的密集组合。会议地点是伯克郡山脉的一个小度假村，现场最多只能有125人参加。这种设置和会议规模是促进个人互动和鼓励研究生和博士后学生积极参与的理想选择。

DESCRIPTION (provided by applicant): This grant seeks funds to hold the "Third International Symposium on Computational Cell Biology" to be held March 19-23, 2005 at the Cranwell Resort and Golf Club in Lenox, MA. Computational Cell Biology is an emerging interdisciplinary field that responds to the need for computational methods to analyze and organize the massive amount of complex experimental data on the structure and function of the cell. Whereas other meetings in computational biology focus on bioinformatics and structural biology, this is the only meeting geared specifically to the use of computational modeling applications in cell biology and primarily targeted to cell biologists. The symposium is being organized by The National Resource for Cell Analysis and Modeling (NRCAM), located in the Center for Biomedical Imaging Technology (CBIT) at the University of Connecticut Health Center. The organizing committee consists of Drs. Leslie M. Loew, Director of NRCAM and CBIT, John Carson, co-Director of NRCAM, and Ann Cowan, Deputy Director of CBIT and head of dissemination and training for NRCAM, who chairs the committee. 2 previous symposia, held in 2001 and 2003, provided a venue for cell biologists to interact with theoreticians and computer scientists, and were highly successful in their scientific content, in initiating a new level of communication among different groups of scientists, and in defining the emerging field of computational cell biology. The continuation of this symposium will help to solidify and extend the community of computational cell biologists and continue to bridge the disciplinary gap in cultures among theoretical and experimental cell biologists. The scientific focus of the meeting is on areas of cell biology for which modeling approaches are currently being developed, or that are ripe for computational modeling approaches. Topic at the meetings will encompass a range of cellular mechanisms including regulation of the cytoskeleton and molecular motors, membrane and protein trafficking, regulation of calcium dynamics, signal transduction pathways, and cell cycle control. In each of these areas researchers using highly quantitative experimental approaches and/or applying mathematical modeling approaches will be invited to speak. The meeting format is an intensive mix of platform sessions, poster sessions and small workshops and tutorials. The venue for the meeting is a small resort in the Berkshire Mountains that is limited to a maximum of 125 on-site participants. This setting and meeting size is ideal for facilitating individual interactions and encouraging active participation by graduate and postdoctoral students.