A5: MOLECULAR BIOLOGY CORE FACILITY

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。由Gabor Mocz博士领导的Frederick Greenwood分子生物学核心设施（MBCF）支持夏威夷大学的生物医学和分子生物学研究和教育项目。MBCF设在太平洋生物科学研究中心（PBRC），该中心提供机构资金，以补充从用户费用中获得的收入。RCMI项目支持基因组学、蛋白质分析和生物信息学等新技术的开发。该设施的分析和合成服务包括DNA测序、DNA片段分析/基因分型、DNA合成、基因表达/DNA微阵列分析、实时定量PCR、SNP分析/基因分型、WAVE核酸片段分析、氨基端蛋白测序、QC Lab-Chip生物分析、遗传和统计分析和数据挖掘以及大分子建模。提供了教育和培训活动，以扩大该设施对潜在用户的接触，并确保研究人员及时了解迅速变化的技术的新发展。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Frederick Greenwood Molecular Biology Core Facility (MBCF), directed by Dr. Gabor Mocz, supports the biomedical and molecular biology research and educational programs of the University of Hawaii. The MBCF is housed in the Pacific Biosciences Research Center (PBRC) which provides institutional funds to supplement the income derived from user fees. The RCMI program supports the development of new technologies in genomics, protein analysis, and bioinformatics. The analytical and synthetic services of the Facility include DNA sequencing, DNA fragment analysis/genotyping, DNA synthesis, gene-expression/DNA micro-array analysis, quantitative real-time PCR, SNP analysis/genotyping, WAVE nucleic acid fragment analysis, amino-terminal protein sequencing, QC Lab-Chip bio-analysis, genetic and statistical analysis and data mining, and macromolecular modeling. Education and training activities are provided to increase the outreach of the facility to potential users and to ensure that researchers are kept abreast of new developments in rapidly changing technologies.