Predoc Training at the Interface Chemistry and Biology

申请者描述(由申请者提供)：本申请申请为耶鲁大学化学/生物学接口的一个新的培训项目申请资金。在过去的五年里，耶鲁大学通过分子、细胞和发育生物学、化学、药理学和分子生物物理与生物化学(MB&B)系的初级和高级职位的新招聘和晋升，有意识地努力增加其在这一领域的代表性。这一扩展极大地增强了我们在这一极其重要的研究领域培训学生的能力。考虑到耶鲁目前在合成和机械化学以及分子生物学和生物化学方面的优势，这些新任命创造了一个与耶鲁几十年来所经历的任何事情都不同的界面培训环境。耶鲁化学生物学项目有来自五个系的25名培训员参加。为12名博士前实习生寻求支持。所有被录取的实习生都将至少拥有相关领域的学士学位。学员将通过申请进入化学系或在非常成功的耶鲁生物和生物医学(BBS)项目中进入一个新的化学生物学轨道。无论入学方式如何，所有学员都将分享共同的第一年经验，包括跨学科课程工作、实验室轮换，以及研究生主任与执行委员会的密切监督和指导。在第一年结束时，学员将从CBP培训师中选择一名论文导师和共同导师，并在第二年开始密集的研究和额外的课程。所有学生至少任教一年，以帮助他们作为教师-学者的培训。增加少数族裔学员人数和提供与研究有关的道德问题教育的方案是这一培训方案的重要组成部分。预计学员将需要5到6年的时间来完成博士学位的培训。培训计划的特点包括跨部门课程工作，包括为新学员特别设计的课程，严格的部门间轮换时间表，在此期间，学员将在耶鲁的三个实验室体验科学，秋季化学生物学计划务虚会，每月讨论最新结果的内部研讨会计划，以及年度化学生物学研讨会。

DESCRIPTION (provided by applicant): This application requests funds for a new training program at the Chemistry/Biology Interface at Yale University. Over the past five years Yale has made a conscious effort to increase its representation in this area through new hires and promotions at the junior and senior levels in the departments of Molecular, Cellular and Developmental Biology, Chemistry, Pharmacology and Molecular Biophysics and Biochemistry (MB&B). This expansion has dramatically enhanced our ability to train students in this exceedingly important research area. Taken with the current strengths in synthetic and mechanistic chemistry and in molecular biology and biochemistry for which Yale is distinguished, these new appointments create an environment for interfacial training that is unlike anything Yale has experienced in decades. The Yale Chemical Biology Program involves 25 trainers from five departments. Support is sought for 12 pre-doctoral trainees. All trainees admitted to the program will have at least a Bachelor's degree in a relevant field. Trainees will enter via an application to the chemistry department or to a new chemical biology track within the very successful Yale Biological and Biomedical Sciences (BBS) program. Regardless of mode of entry all trainees will share a common first year experience involving interdisciplinary course work, laboratory rotations, as well as close supervision and guidance from the director of graduate students in conjunction with the executive committee. At the end of their first year, trainees will chose a thesis advisor and co-mentor from among the CBP trainers and begin intensive research with additional courses in their second year. All students teach for at least one year to aid in their training as teacher-scholars. Programs for increasing the number of minority trainees and for providing education in ethical issues related to research represent important parts of this training program. It is expected that trainees will require 5 to 6 years to complete their training toward the Ph.D. Special features of the training program include interdepartmental course work, including specially designed courses for the new trainees, a rigorous interdepartmental rotation schedule during which the trainee will experience science in three laboratories at Yale, a Fall Chemical Biology Program Retreat, a monthly in-house seminar program for discussion of recent results and an annual Chemical Biology Symposium.