IMAGE GUIDED THERAPY CENTER

描述（由申请人提供）： 我们正在申请资金，在布里格姆妇女医院建立一个国家生物医学资源中心，用于图像引导治疗（IGT）。IGT中心提出under jr这个应用程序将提供一个独特的，集中的基础设施，为临床研究者，生物医学！工程师和基础科学家在促进和推进IGT的方法和相关的临床应用。我们将在五个独立的TRD核心项目中开发和提供新的创新技术：1）计算核心; 2）成像核心; 3）MRI引导治疗核心; 4）图像引导神经外科核心;和5）聚焦超声治疗核心。这些关键的研究举措代表了资源的技术和临床基础设施。他们预计将对未来的几种IGT方法和临床应用产生重大影响;并将联合收割机力量与10个内部和7个外部独立资助的合作项目相结合，以解决IGT的各种基本技术或临床问题。这些集体的科学努力包括开发图像处理和显示工具（3D Slicer，交互式和自适应平台，高性能计算）;动态和自适应MR成像方法;新的治疗技术（MRI引导聚焦超声）;图像引导机器人;以及从脑肿瘤手术到前列腺干预的几种临床应用。所有IGT开发和应用程序将在现场与我们的合作者进行测试，或直接作为服务分发给不断增长的IGT社区。我们的总体目标是建立一个具有国家性质的中心，通过培训和传播本资源中正在开发的新技术和方法，有效地覆盖广泛的支持者。

DESCRIPTION (provided by applicant): We are requesting funds to establish a national Biomedical Resource Center in Image-guided Therapy (IGT) at the Brigham & Women's Hospital. The IGT Center proposed undejr this application will provide a unique, centralized infrastructure for clinical investigators, biomedica! engineers, and basic scientists in promoting and advancing IGT methods and related clinical applications. We will develop and make available new innovative technologies in five discrete TRD Core Projects: 1) the Computational Core; 2) the Imaging Core; 3) the MRI-guided Therapy Core; 4) the Image-Guided Neurosurgery Core; and 5) the Focused Ultrasound Therapy Core. These key research initiatives represent the technical and clinical infrastructure of the Resource. They are anticipated to have significant effect on several future IGT methods and clinical applications; and will combine forces with 10 internal and 7 external, independently funded Collaborations that address various essential technical or clinical aspects of IGT. These collective scientific efforts include the development of image processing and display tools (3D Slicer, interactive and adaptive platforms, high performance computing); dynamic and adaptive MR imaging methods; novel therapy techniques (MRI-guided focused ultrasound); image-guided robotics; and several clinical applications from brain tumor surgery to prostate interventions. All IGT developments and applications will be tested either on site with our collaborators, or distributed directly as a service to the growing IGT community. Our overarching goal is to create a Center that is national in character reaching effectively across a broad range of constituencies through training in and dissemination of the novel technologies and methods under development in this Resource.