Enhancing Exercise Participation in Overweight Women

描述(由申请人提供)：这项研究的主要目标是检验与标准行为干预(SBWP)相比，在治疗的初始阶段(前采用)或在治疗的维持阶段(前维持)加强运动干预是否能改善行为减肥计划中的长期减肥效果。这项研究的次要目标包括检查SBWP与收养前和维持前相比在心肺功能、体脂百分比和体脂分布、体力活动和饮食摄入量方面的变化。我们还将研究身体活动行为的潜在中介因素。 在过去的几十年里，肥胖症的流行率一直在上升，现在估计超过50%的成年人超重。运动已被证明是行为减肥计划的重要组成部分，而且运动似乎与长期减肥的改善有关。然而，根据我们研究的数据，似乎有一些关键时期的干预应该集中在锻炼部分。其中一个阶段似乎是在治疗的采用阶段，因为在治疗早期参加运动预示着长期的体重减轻。或者，似乎确实存在锻炼开始减少、体重开始增加的关键时期。使用一组行之有效的改善运动的策略，我们将在我们建议的强化干预(前采用和前维持)中针对这两种方法，并检查这两种方法中是否有一种方法比SBWP更有效地实现长期减肥。 据推测，在18个月的干预过程中，与SBWP相比，前收养和前维护都会改善体重减轻、体力活动、健康和身体成分。体重、健康和身体成分的评估将在0、6、12和18个月进行。为了更好地了解潜在的中介因素对运动接受和参与的影响，我们建议在0、3、6、9、12、15和18个月时评估这些因素和体力活动。据信，这项拟议的研究将改善超重女性的运动参与度，从而改善肥胖症的长期治疗。

DESCRIPTION (provided by applicant): The primary goal of this study is to examine whether enhancing the exercise intervention either during the initiation phase of treatment (EX-ADOPT) or during the maintenance phase of treatment (EX-MAINTAIN) improves long-term weight loss in a behavioral weight loss program compared to a standard behavioral intervention (SBWP). Secondary aims of this study include examining changes in cardio-respiratory fitness, percent body fat and body fat distribution, physical activity, and dietary intake in SBWP compared to both EX-ADOPT and EX-MAINTAIN. We will also examine potential mediators of physical activity behaviors. The prevalence of obesity has been increasing over the past few decades, and it is now estimated that in excess of 50 percent of adults are overweight. Exercise has been shown to be an important component of behavioral weight loss programs, and exercise appears to be associated with improvements in long-term weight loss. However, based on data from our studies, it appears that there may be key periods where the intervention should focus on the exercise component. One period appears to be during the adoption phase of treatment, as exercise participation early in treatment is predictive of long-term weight loss. Alternatively, it does appear that there are critical periods when exercise begins to decrease and weight begins to increase. Using a combination of proven strategies for improving exercise, we will target these two approaches in our proposed enhanced interventions (EX-ADOPT and EX-MAINTAIN), and examine if either of these approaches is more effective than SBWP for long-term weight loss. It is hypothesized that both EX-ADOPT and EX-MAINTAIN will improve weight loss, physical activity, fitness, and body composition compared to the SBWP across an 18-month intervention. Assessment of weight, fitness, and body composition will occur at 0,6,12,and 18 months. To better understand the impact of potential mediators on exercise adoption and participation in this study, we propose to assess these factors and physical activity at 0,3,6,9,12,15, and 18 months. It is believed that this proposed study will lead to improvements in exercise participation in overweight women, which will result in improvements in the long-term treatment of obesity.