Short Course: Integrative and Organ Systems Pharmacology

描述（由申请人提供）：拟议的综合与器官系统药理学短期课程旨在为研究生，博士后，初级教师和工业科学家提供讲座，示范和全动物实践经验。这已经成为一个日益重要的问题，因为越来越多的药理学培训计划已经成为专门的细胞和分子性质。该课程将在夏季开设两周，重点是心血管和神经药理学。讲座内容包括：IACUCs的功能、动物的人道待遇和相应的法规、心血管生理学、药理学和神经药理学的背景资料。将使用仪器动物（狗，兔子）进行全动物心血管实验，并使用各种技术来检查啮齿动物的伤害感觉和认知。分离的血管材料和心脏将用于器官系统研究。在这些实验中使用的药物将与在仪器动物中使用的药物相同。此外，还将有1.5天的时间留给学生选择的选修课、动手实践和重点体验。有兴趣的学生可以选择第三周实习。

DESCRIPTION (provided by applicant): The proposed Short Course in Integrative and Organ Systems Pharmacology is designed to provide graduate students, postdocs, junior faculty and industrial scientists with lectures, demonstrations and hands on experiences with whole animal. This has become an issue of increasing importance as more and more pharmacology training programs have become exclusively cellular and molecular in nature. The course to be offered over two weeks in the summer will focus on cardiovascular and neuropharmacology. Lectures will be provided on the functioning of IACUCs, the humane treatment of animals and regulations appropriate to this, background material on cardiovascular physiology, pharmacology and neuropharmacology. Instrumented animals will be used (dogs, rabbits) for whole animal cardiovascular experiments and various techniques will be used for examining nociception and cognition in rodents. Isolated vascular material and hearts will be used for organ system studies. The drugs used in these experiments will be the same as those used in the instrumented animals. There will also be 1.5 days set aside for elective, hands on, focused experiences selected by the students. An optional third week internship will be available for interested students.