Surgical Monitor for Detection of Spinal Cord Injury

描述(申请人提供)：脊柱手术期间的体感诱发电位(SEP)监测与主要神经缺陷减少61%相关。然而，对信号的视觉解释并不总是准确的，而且已经证明了一条重要的学习曲线。因此，我们着手开发一种新型的SEP监护仪，配备最新的无线和数字信号处理技术，以连续监测脊髓功能。我们建议开发一套技术工具箱，以显著推进手术中的脊髓评估，包括： 基于单扫频抑制和滤波的综合降噪 SEP各光谱分量相干性的研究 无线多通道刺激监测一体化 临床研究中对下一代实时监护仪的评估 我们的愿景是将这些硬件和软件创新转化为有用的设备，以帮助临床医生改善接受脊柱手术的患者的预后。

DESCRIPTION (provided by applicant): Somatosensory evoked potential (SEP) monitoring during spinal surgery has been associated with a 61% reduction in major neurological deficits. However, visual interpretation of signals is not always accurate, and a significant learning curve has been demonstrated. Therefore, we embarked on a course to develop a novel SEP monitor equipped with the latest in wireless and digital signal processing technology to continuously monitor spinal cord function. We propose the development of a toolbox of techniques which will significantly advance spinal cord assessment during surgery, including:  Integration of noise reduction via single-sweep rejection and filtering  Investigation of the coherence of individual spectral components of the SEP and  Incorporation of wireless multi-channel stimulation & monitoring  Evaluation of the resulting next-generation real-time monitor in a clinical study It is our vision to translate these hardware and software innovations into a useful device to assist the clinician in improving the outcome of the patient undergoing spinal surgery.