Project to be confirmed after rotation year

释放人工智能在合成基因组学中的力量：这个博士项目结合了合成基因组学和人工智能，以解锁基因组结构的见解。我们的目标是通过利用先进的基因操作技术（如CRISPR/Cas9）和人工智能的力量来简化基因组工程过程。我们的项目采用生成深度神经网络，类似于大型语言转换器，来开发基因组组织的生成模型。该模型将使用裂殖酵母进行实验验证，以创建最小和有效的基因组优化蛋白质生产。这个跨学科的项目有望彻底改变我们对基因组组织的理解，可能影响各种生物技术应用。

Unleashing the Power of AI in Synthetic Genomics: This PhD project combines syntheticgenomics and artificial intelligence to unlock genome architecture insights. We aim tostreamline the genome engineering process by utilising advanced gene manipulationtechniques like CRISPR/Cas9 and the power of AI. Our project employs generative deepneural networks, akin to large language transformers, to develop generative models ofgenome organisation. The models will be experimentally validated usingSchizosaccharomyces pombe to create minimal and efficient genomes optimised forprotein production. This interdisciplinary project promises to revolutionise ourunderstanding of genome organisation, potentially impacting various biotechnologyapplications.