Howard/Hopkins Cancer Center Partnership

由霍华德大学癌症中心（HUCC）和约翰霍普金斯综合癌症中心（JHCCC）、马里兰州和哥伦比亚特区服务的地区，在美国50多年来一直是癌症死亡率最高的地区之一。这些地区的少数民族居民受到癌症的影响不成比例，癌症已成为巴尔的摩、马里兰州和华盛顿，华盛顿特区非洲裔美国人发病率和死亡率的主要原因。为了解决这一问题，HUCC和JHCCC已开始合作，以增加与癌症有关的筛查诊断、预防、治疗和支持性护理方面的富有成效的研究，特别关注非裔美国人的癌症。HUCC/JHCCC伙伴关系，开始作为一系列的合作努力，涉及教师从每个机构组织成针对高优先领域的群体，自1999年9月以来一直由国家癌症研究所（NCI）的JHCCC核心补助金的补充资金支持。迄今为止，在HUCC/JHCCC伙伴关系的规划阶段所取得的成功，以及在包括前列腺癌、胃肠道癌和乳腺癌在内的几个领域的合作研究进展，促使提交了这项赠款，以确保进一步加强伙伴关系活动的资金。这项赠款提案的主要目的是继续发展HUCC和JHCCC之间的可持续伙伴关系，以加强这两个机构的研究，培训，教育和推广任务。为了实现这一目标，HUCC/JHCCC伙伴关系将致力于建立针对非裔美国人癌症的HUCC研究师资和科学计划，加强JHCCC涉及非裔美国人的基于人群的癌症研究，增加HUCC非裔美国人职业研究人员的研究培训和职业发展机会，并改善JHCCC的教育和外展项目，重点关注非裔美国人的职业发病率和死亡率。该提案寻求对3个研究项目、2个试点研究项目、1个试点教育项目和HUCC核心基础设施的支持，沿着额外资金，以进一步规划和发展HUCC/JHCCC伙伴关系。在HUCC/JHCCC伙伴关系所需的5年支持期间，随着这些初步研究和教育活动的进展，以竞争独立资金，新的项目，计划和高度优先发展的资源将得到确定和支持。

The regions served by the Howard University Cancer Center (HUCC) and Johns Hopkins Comprehensive Cancer Center (JHCCC), Maryland and the District of Columbia, have had among the highest cancer death rates in the United States for more than fifty years. Minority residents of these regions have been disproportionately affected by cancer, and cancer has become a leading cause of morbidity and mortality for African-Americans in both Baltimore, Maryland, and Washington, D.C. To address this problem, HUCC and JHCCC have embarked on a partnership to increase productive research in screening diagnosis, prevention, treatment, and supportive care as it relates to cancer, with a special focus on cancer in African-Americans. The HUCC/JHCCC partnership, which began as a series of collaborative efforts involving faculty from each institution organized into groups targeting high priority areas, has been supported since September of 1999 by supplemental funds for the JHCCC core grant from the National Cancer Institute (NCI). The success realized thus far during the planning phases of the HUCC/JHCCC partnership, with c9ollaborative research progress in several areas, including prostate cancer, gastrointestinal cancer, and breast cancer, has prompted the submission of this grant in an attempt to secure funds to further augment partnership activities. The major aim of this grant proposal is to continue the development of a sustainable partnership between HUCC and JHCCC that enhances the research, training, education, and outreach missions of both institutions. To accomplish this goal, the HUCC/JHCCC partnership will work to build the research faculty and scientific programs at HUCC directed at cancer in African-Americans, to enhance population-based cancer studies at JHCCC involving African-Americans, to increase opportunities for research training and career development of African-American career researchers at HUCC, and to improve education and outreach programs at JHCCC focused on career morbidity and mortality among African- Americans. The proposal seeks support for 3 research projects, 2 pilot research proj4ects, 1 pilot educational program, and core infrastructure at HUCC, along with additional funds for further planning and development of the HUCC/JHCCC partnership. Over the 5 years of support requested for the HUCC/JHCCC partnership, as these initial research and educational activities progress to compete for independent funding, new projects, programs, and resources of high priority for development will be identified and supported.