Research Symposium on Functional Abdoninal Pain in Children

描述（由申请人提供）：第一届研讨会“儿童功能性腹痛和肠易激综合征（IBS）的新见解：多学科方法”旨在汇集基础和临床科学家，他们的主要临床和研究兴趣涉及儿童功能性腹痛，IBS和相关疼痛综合征的病理生理学，评估和治疗。本次研讨会将1)确定儿童功能性胃肠疾病（FGID）未来研究的研究目标，2)促进各种相关学科的国内外专家之间的互动和信息共享，3)确定这些疾病的评估和治疗的最新状态，4)建立一个多学科合作研究联盟。未来的专题讨论会将重点报道与儿童FGID相关的正在进行的研究，并制定进一步的合作项目。本次研讨会将在北美儿科胃肠病学、肝病学和营养学会（NASPGHAN）的主持下举行。研讨会将邀请演讲者（功能性腹痛和肠易激综合征以及其他儿童疼痛综合征相关基础、转化和临床研究的高级和初级专家）、专家“讨论者”、初级教师和实习生。本次研讨会的总体目标如下：为了更好地了解中枢和肠神经系统、胃肠道平滑肌和特定细胞类型在功能性腹痛和IBS病理生理学中的作用，将基础科学家聚集在一起研究FGID的细胞和分子方面。将临床研究人员聚集在一起，讨论儿童功能性腹痛和肠易激综合征的遗传学、病理生理学、诊断和治疗策略。3. 介绍在成人功能性腹痛和肠易激综合征研究中处于领先地位的研究人员的观点，以利用他们的专业知识，揭示成人和儿童的疾病机制、临床表现和治疗之间的共同点或差异。通过确定儿童腹痛和肠易激综合征的具体方面，将推荐具体的研究领域。4. 介绍儿童其他疼痛综合征的临床方面的最新信息，并提供一个论坛，让儿童其他疼痛综合征的主要临床研究者可以分享他们的专业知识，并允许与那些参与功能性腹痛研究的人交流，以确定共同的途径并促进合作。5. 为有前途的年轻科学家（研究生、博士后实习生和处于职业发展早期阶段的教师）、女性科学家和代表性不足的少数群体提供机会，与功能性腹痛和IBS领域的知名研究者和专家临床医生讨论他们的研究。此外，本次论坛将提供一个独特的机会，与特邀演讲者进行深入讨论，以促进基础科学家和转化/临床科学家之间的交流。6. 制定合作研究的研究议程，以确定儿童功能性腹痛的病理生理学和治疗策略。7. 向NASPGHAN会员介绍儿童功能性腹痛和肠易激综合征的最新进展。

DESCRIPTION (provided by applicant): The First Symposium "New insights into childhood functional abdominal pain and Irritable Bowel Syndrome (IBS): a multidisciplinary approach" is designed to bring together basic and clinical scientists whose major clinical and research interest relates to the pathophysiology, evaluation and treatment of childhood functional abdominal pain, IBS, and related pain syndromes. This Symposium will 1) identify research targets for future studies of pediatric functional gastrointestinal disorders (FGID), 2) foster interaction and information sharing among national and international experts in a variety of relevant disciplines, 3) define the state of the art in the evaluation and treatment of these disorders and 4) establish a consortium for multidisciplinary collaborative studies. Future Symposia will focus on reporting ongoing studies related to pediatric FGID and developing further collaborative projects. This symposium will be held under the auspices of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). The Symposium will host invited speakers (both senior and junior experts in basic, translational, and clinical research relevant to functional abdominal pain and IBS, as well as in other pain syndromes in children), expert "discussants", junior faculty and trainees. The following are the Overall Goals of the symposium: 1. To bring together basic scientists addressing cellular and molecular aspects of FGID in order to better understand the roles of the central and enteric nervous systems, gastrointestinal smooth muscle and specific cell types in the pathophysiology of functional abdominal pain and IBS 2. To bring together clinician-investigators addressing the genetics, pathophysiology, diagnosis and treatment strategies of functional abdominal pain and IBS in children. 3. To present the perspective of researchers who are leaders in the study of functional abdominal pain and IBS in adults, in order to take advantage of their expertise, and to uncover points of commonality or disparity between the disease mechanisms, clinical presentation and treatment in adults and in children. By identifying the aspects that are more specific to childhood abdominal pain and IBS, specific areas for research will be recommended. 4. To present the latest available information on clinical aspects of other pain syndromes in children, and to provide a forum in which leading clinical investigators of other pain syndromes in children may share their expertise and allow cross-fertilization with those involved in the study of functional abdominal pain, in order to identify common pathways and stimulate collaboration. 5. To provide opportunities for promising young scientists (graduate students, postdoctoral trainees and faculty at an early stages of their career development), female scientists, and underrepresented minorities to discuss their research with established investigators and expert clinicians in the field of functional abdominal pain and IBS. In addition, this forum will provide a unique opportunity for in-depth discussions with invited speakers to stimulate communication between basic and translational/clinical scientists. 6. To develop a research agenda for collaborative studies to define the pathophysiology and treatment strategies for childhood functional abdominal pain. 7. To educate the NASPGHAN membership on the state of the art of functional abdominal pain and IBS in children.