Conference Series: From Bedside to Bench

描述（由申请人提供）：与最初的资助标题“从床边到实验室”保持一致，我们强调会议的转化方面，特别是使用临床问题来框架、定义和推动基础研究，并促进基础和临床研究者之间的互动。该方案延续了原方案的许多成功特征；根据老年病学社区和NIA的意见制定的主题，有充足时间进行互动的多学科会议，由年轻研究者、少数族裔研究者和传统老龄化研究社区内外的知名领导者参与，通过AGS年会的专题讨论会进行传播，并通过美国老年病学学会杂志（JAGS）以及其他媒体发表。根据过去一年AGS和NIA制定的优先事项，我们提出2007-2009年要解决的三个新课题；1)“思维、运动和感觉：衰老的认知、情绪和运动障碍是否有重叠的因果机制？”，2)“衰老的特发性疲劳”，3)“炎症和营养代谢：相互作用是有效干预的关键”。这是一份代表美国老年病学会（AGS）与美国国家老龄研究所（NIA）老年病学和临床老年学分会合作的为期三年的U13合作会议资助申请。本次会议奖助金计划的使命与最初的提议保持不变；“加强对临床迫切关注的临床老年病学问题的研究，或有可能大大改善老年人的临床护理或预防”。我们的长期目标仍然是“将研究成果转化为临床护理，以改善老年人的健康状况。”

DESCRIPTION (provided by applicant): In keeping with the original grant title "Bedside to Bench", we emphasize the translational aspect of the conferences, especially the use of clinical issues to frame, define and drive basic inquiry, and to promote interactions between basic and clinical investigators. This proposal continues many of the successful features of the original program; topics developed with input from the geriatrics community and the NIA, multidisciplinary conferences with ample time for interaction, participation by young investigators, minority investigators and established leaders from within and outside the traditional aging research community, dissemination through Symposia at the Annual Meeting of AGS and publication through the Journal of the American Geriatrics Society (JAGS), as well as other media. Based on priorities developed by AGS and NIA over the last year, we propose three new topics to be addressed in 2007-2009; 1) "Thinking, moving and feeling: do cognitive, mood and movement disorders of aging have overlapping causal mechanisms?", 2) "Idiopathic Fatigue of Aging," and 3) "Inflammation and nutrient metabolism: interaction as a key to effective intervention." This is an application for a three year U13 cooperative conference grant on behalf of the American Geriatrics Society (AGS) in cooperation with the Geriatrics and Clinical Gerontology branch of the National Institute on Aging (NIA). The mission of this conference grant program remains unchanged from the initial proposal; "to heighten research attention on clinical geriatrics issues that are of pressing concern clinically or have the potential to greatly improve clinical care or prevention for older adults". Our long term goal remains to "translate research results into clinical care that will improve the health outcomes of older adults."