Immunohematology/Transfusion Medicine Research Training

描述(由申请人提供)： 这项建议是为了续期我们于2001年开始的免疫血液学和输血医学研究培训补助金。它为已经完成临床培训的医学博士和医学博士提供了一个高度有组织的场所，在教学框架内，在这个未被充分代表的领域获得密集的研究经验，目标是培养富有成效的内科科学家。T32还培养希望成为博士临床医生的博士-实验室医学科学家，具有基础研究技能和对临床翻译需求的理解。由耶鲁大学实验室医学系赞助，它还为具有最少研究经验的纯MD候选人提供了同时攻读额外学位的机会，要么是研究医学博士学位，要么是生物医学工程硕士学位。所有学员都有专门的“培训委员会”(类似于研究生论文委员会)进行核心实验室体验；特别研讨会系列是核心体验的补充。我们的跨学科教师包括来自7个不同主要部门的22位资金雄厚、经验丰富的导师，他们都有长期的合作历史，他们的实验室在同时培养博士后、博士后和博士后方面经验丰富。在T32的第一个周期中，将有五名学员-两名毕业，其余的仍在进行中。两名毕业生(1名医学博士，1名博士)都获得了教职员工职位，其中一人获得了K08奖项。在正在进行的3名博士中(2名医学博士，1名博士)，两名医学博士正在攻读更高的研究方向学位(1名调查医学博士，另一名生物工程硕士)。有3名男性和2名女性，一名受训人员有波多黎各血统。他们在代表两个不同部门的4个不同实验室工作过。根据这一经验，我们要求将博士后培训名额从2个增加到4个--我们已经有了优秀的候选人，他们可能会在2008-09年度占据所要求的4个名额。包括其他资助机制的受训人员在内，共有32名受训人员参加了我们的“大”免疫血液学研究项目。我们认为这个项目满足了耶鲁大学和全国的一个重要的研究培训需求。(摘要结束)

DESCRIPTION (provided by applicant): This proposal is for renewal of our research training grant in Immunohematology and Transfusion Medicine initiated in 2001. It provides a highly organized venue for MDs and MD/PhDs who have completed their clinical training to obtain an intense research experience in this underrepresented field, within a didactic framework, with the goal of generating productive physician-scientists. The T32 also trains PhDs who wish to become PhD clinician-scientists in Laboratory Medicine with skills in basic research combined with an understanding of clinical translational needs. Sponsored by the Yale Department of Laboratory Medicine, it also provides an opportunity for MD-only candidates with minimal prior research experience to simultaneously pursue an additional degree, either the Investigative Medicine PhD or a Master's in Biomedical Engineering. The core laboratory experience is carried out with all trainees having a dedicated 'training committee' (similar to a graduate student thesis committee); special seminar series complement the core experience. Our interdisciplinary faculty includes 22 well-funded, experienced mentors from 7 different primary departments, all of whom, have a long history of collaboration and whose laboratories are experienced in the simultaneous training of post-doc MDs, post-doc PhDs and pre-doc PhDs. In the first cycle of the T32, there will have been five trainees - two graduated and the remainder ongoing. Both graduates (1 MD, 1PhD) have obtained academic faculty positions - one has a K08 award. Of the 3 ongoing (2 MD, 1PhD), the two MDs are pursuing higher research-directed degrees (1 Investigative Medicine PhD, the other a Master's in Bioengineering). There are 3 men and 2 women, one trainee is of Puerto Rican heritage. They have worked in 4 different laboratories representing 2 distinct departments. Based on this experience, we are requesting an increase from 2 to 4 postdoctoral training slots - we already have excellent candidates in the pipeline who would potentially occupy the requested 4 slots through 2008-09. In total, including research trainees on other funding mechanisms, there are 32 trainees in our 'greater' immunohematology research program. We see this program as filling an important research training need both at Yale and nationally. (End of Abstract)