Heart Failure Clinical Research Network

描述（由申请人提供）： 拟议的心力衰竭区域临床中心（HF-RCC）申请提供了一个独特的机会，可以访问执业医生以及农村和少数民族外展，以支持心力衰竭研究和教育。该网络是由莫尔豪斯医学院社区医生网络（CRN）开创的学术-社区医生伙伴关系，以促进临床研究和实践为基础的质量改进。该网络允许在社区实践层面无缝集成NIH支持的临床协议。HF RCC建立在这种模式的基础上，将北亚特兰大最大的心脏病学团体实践与南亚特兰大地铁和周围农村社区最大和最古老的少数民族拥有的心脏病学实践结合在一起，以领先的实践和研究而闻名于美国东南部。从心力衰竭登记数据库中可以明显看出该网络的非凡地理范围、其社会经济和种族多样性，该数据库的摘要包含在本申请中。最后，与圣约瑟夫医院和格雷迪医院，大型三级保健中心，分别在全国范围内获奖的心血管护理和优秀的护理提供服务不足，提供前所未有的机会和信誉，影响心血管护理和健康差距。男男性接触者的长期使命，以促进公平照顾所有人是最终的引擎和激情，推动网络。事实上，参与的实践和医院都将这一承诺作为他们对社区医生网络感兴趣的主要动力。我们根据我们在招募和留住难以接触的患者人群方面的经验和专业知识提出了一个基础设施。这两个项目为充分利用该网络的知识和基础设施能力提供了机会。这两个项目都利用了我们RCC中心力衰竭患者人群的规模以及研究人员的专业知识。项目一利用了我们对高血压性心脏病和心力衰竭中重塑的研究兴趣，并利用了我们小组对以下作用的兴趣： NO参与心血管重构。第二个项目主要是基于我们的专业知识， Nicholas Chronos博士是临床前和早期临床试验中基于细胞的治疗的合作者。拟议的临床技能发展核心整合了现有的临床培训资源，如 在MSM临床研究计划成功的科学硕士和心血管后的追捧 圣约瑟夫研究所的研究培训计划。总之，我们提出了一个非常独特的应用程序，它应该作为未来合作研究网络的模型，寻求积极参与和整合社区实践，这是NIH的一个关键目标。(End摘要）

DESCRIPTION (provided by applicant): The proposed Heart Failure Regional Clinical Center (HF-RCC) application provides a unique opportunity to access practicing physicians as well as rural and minority outreach to support heart failure research and education. The network is an academic - community physicians partnership pioneered by the Morehouse School of Medicine Community Physicians' Network (CRN), to promote clinical research and practice based quality improvement. The network allows seamless integration of NIH supported clinical protocols at the community practice level. The HF RCC builds up on this model by bringing together the largest Cardiology group practice, in North Atlanta, known in the southeast USA for leading edge practice and research with 2 of the largest and oldest minority owned Cardiology practices in the South Metro Atlanta and surrounding rural communities. The extraordinary geographic reach of the network, its socioeconomic and ethnic diversity is evident from the Heart Failure Registry database, a summary of which is included with this application. Finally, the affiliations with St. Joseph's Hospital and Grady Hospital, large tertiary care centers, respectively known nationally for award winning cardiovascular care and outstanding care delivery to the underserved, provide unprecedented opportunity and credibility to impact cardiovascular care and health disparities. The longstanding mission of MSM to promote equitable care for all is the ultimate engine and passion that drives the network. Indeed participating practices and hospitals have cited this commitment as a key motivator for their interest in the Community Physicians' Network. We have proposed an infrastructure based on our experience and expertise in recruiting and retaining difficult to reach patient populations. The two projects provide an opportunity to fully exploit the intellectual and infrastructure capacity of the Network. Both projects capitalize on the size of the Heart Failure patient population in our RCC, as well as expertise of investigators. Project one draws upon our research interest in remodeling in hypertensive heart disease and heart failure, and also takes advantage of our group's interest in the role of NO in cardiac and vascular remodeling. The second project is largely based on the expertise of our collaborator, Nicholas Chronos, MD in cell based therapies in preclinical and early phase clinical trials. The proposed clinical skills development core integrates existing clinical training resource such as the successful Master of Science in Clinical Research Program at MSM and the sought after cardiovascular research training program at St. Joseph's Research Institute. In summary, we have proposed a very unique application which should serve as a model for future collaborative research networks that seek to actively engage and integrate community practices, a key stated goals of the NIH to map initiative. (End of Abstract)