Chronic Prostatitis Collaborative Research Network

本次申请的目标是在UCLA建立临床试验中心HarborlUCLA医疗中心， 马丁·路德·金-德鲁医学中心，将参与协作，多地点临床试验 由新成立的NIDDK赞助的慢性前列腺炎合作研究网络赞助 （CPCRN）。作为一个CPCRN网站，加州大学洛杉矶分校将 (1)参与随机对照临床试验的设计，以治疗相关症状 慢性前列腺炎，又称慢性盆腔疼痛综合征（CPPS） (2)制定和进行辅助研究，以进一步了解CPPS (3)确定患者亚组之间对治疗的反应是否不同，包括 新诊断和慢性、长期CPPS患者 (4)招募足够数量的CCPS患者，包括足够数量的新 诊断病例，进入这些临床试验 (5)与其他CPCRN调查人员，包括数据协调中心，共同分析和 解释试验结果 (6)参加新成立的泌尿系统慢性盆腔疼痛协作组 促进间质性膀胱炎和慢性前列腺炎临床试验的有效进行 本研究将根据以下因素，对泌尿系慢性盆腔疼痛综合征进行临床相关定义： 这些和其他相关临床研究的临床结果。加州大学洛杉矶分校的网站已经证明， 招募少数民族受试者参与CPPS研究（包括临床试验）的经验 和其他泌尿系统疾病。加州大学洛杉矶分校的网站将建立在其经验作为一个宪章网站在第一 实现第二次党代会提出的目标。

The goal of this application is to establish a clinical trial center at UCLA, HarborlUCLA Medical Center, and Martin Luther King-Drew Medical Center that will participate in collaborative, multi-site clinical trials sponsored by a newly established NIDDK-sponsored Chronic Prostatitis Collaborative Research Network (CPCRN). As a CPCRN site, UCLA will (1) participate in the design of randomized controlled clinical trials to treat the symptoms associated with chronic prostatitis, also known as chronic pelvic pain syndrome (CPPS) (2) develop and conduct ancillary studies, which will provide further understanding of CPPS (3) determine if there is a different response to therapy between sub-groups of patients, including newly diagnosed and chronic, long-term patients with CPPS (4) recruit sufficient numbers of patients with CCPS, including an adequate number of newly diagnosed cases, into these clinical trials (5) jointly work with other CPCRN investigators, including a Data Coordinating Center, to analyze and interpret the results of the trials (6) participate in a newly established Urological Chronic Pelvic Pain Syndromes Collaborative Group to facilitate the efficient conduct of clinical trials in both interstitial cystitis and chronic prostatitis The study will develop a clinically relevant definition of the urologic chronic pelvic pain syndromes, based on the clinical findings from these and other related clinical studies. The UCLA site has demonstrated experience in recruiting minority subjects to participate in research studies, including clinical trials, for CPPS and other urologic conditions. The UCLA site will build upon its experience as a charter site in the first CPCRN to achieve the goals set out by the second.