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Protein Microcharacterization Facility

Protein Microcharacterization Facility
蛋白质微观表征设备
批准号:
7330676
负责人:
Kenneth Tomer
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
在LSB的质谱学工作组内已经建立了一个基于质谱学的蛋白质微观表征设施。该设施的目的是提供最先进的蛋白质质谱学表征。这包括通过凝胶电泳法分离的蛋白质,从表达系统获得的蛋白质,从免疫沉淀实验中分离的蛋白质,以及翻译后修饰和加合物的鉴定。该设施还与其他小组合作,从二维凝胶电泳中提供基于MS的蛋白质组学鉴定。此外,项目管理基金还开始每月举办一次用户论坛,并就开放获取MALDI/TOF仪器的使用进行培训。
英文摘要
A mass spectrometry-based Protein Microcharacterization Facility has been established within the Mass Spectrometry Workgroup in LSB. The purpose of the Facility is to provide state-of-the-art mass spectrometric characterization of proteins. This includes proteins separated by gel electrophoresis, obtained from expression systems, isolated from immunoprecipitation experiments, and identification of posttranslational modifications and adducts. The Facility also provides MS-based proteomics identifications from 2-D gel electrophoresis in collaboration with other groups. Additionally, the PMCF has begun a monthly User's Forum and training on use of open access MALDI/TOF instrumentation.
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