"Microscopy and Immunohistochemistry Core"

神经科学显微镜和免疫组织化学核心的长期目标是提供一种状态- 这一先进的设施将使神经科学研究人员能够将神经系统结构和 功能。梅哈里医学院的神经学家们正在探索神经质是如何 系统对可能引发炎症过程的环境和内部应激源做出反应，并 神经退行性变。尤其令人感兴趣的是基因和环境如何相互作用的问题 导致神经退行性疾病。神经科学显微镜的具体目标和 免疫组织化学的核心将是： 1.提供神经形态服务，满足超过80%的 Meharry的神经科学实验室，从而减少了与使用 偏远的设施； 2.将神经系统形态研究的相关成本降低20%： 3.确保Meharry医学院的研究人员可以通过电子期刊访问排名前10位的期刊 发表神经科学研究成果。 神经生物学和神经毒理学分部主席克里维尔·G·查尔顿博士将领导神经科学 显微镜和免疫组织化学设施。将招聘一名训练有素的博士级别的核心主任 工厂的日常管理。核心主任还将实施一项持续的培训方案 适用于调查人员、研究人员和受训人员。由于最近基础科学的重组 各部门、许多微观和细胞/组织处理资源可用于启动这一核心 设施。这包括一台新的共焦显微镜、一个回旋显微镜、显微切片机和常规组织化学。 补给。有必要获得新的荧光显微镜、图像分析软件和 加强神经科学电子期刊的收藏。

The long-range goal of the Neuroscience Microscopy and Immunohistochemistry Core is to provide a stateof- the-art facility that will enable neuroscience investigators to correlate nervous system structure and function. Neuroscientists at Meharry Medical College are exploring various aspects of how the nervous system responds to environmental and internal stressors that may induce inflammatory processes and neuro-degeneration. Of particular interest is the question of how genes and the environment interact to cause neurodegenerative disease. The specific aims of the Neuroscience Microscopy and immunohistochemistry Core will be to: 1. Provide neuro-morphological services that will accommodate the needs of greater than 80% of the neuroscience laboratories at Meharry, thereby decreasing the turn-around time associated with using a remote facility; 2. Decrease by 20% the costs associated with doing morphological studies in the nervous system: and 3. Insure that Meharry Medical College investigators have e-journal access to the top 10 journals that publish neuroscience research results. Dr. Clivel G. Charlton, Chair of the Division of Neurobiology and Neurotoxicology will direct the Neuroscience Microscopy and Immunohistochemistry facility. A trained Ph.D. level Core Director will be recruited for the day-to-day management of the facility. The Core Director will also implement an ongoing training program for investigators, research staff and trainees. As a result of the recent re-organization of the basic science departments, a number of microscopic and cell/tissue processing resource are available to initiate this core facility. This includes a new confocal microscope, a cyrostat, microtome, and routine histochemistry supplies. There is the need to acquire a new fluorescence microscope, image analysis software and enhance the neuroscience e-journal collection.