UCLA MULTICENTER AIDS COHORT STUDY: NATURAL HISTORY OF AIDS IN HOMOSEXUAL MEN

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。多中心艾滋病队列研究是一项前瞻性队列研究，始于1984年，旨在跟踪HIV血清阳性和血清阴性男性。加州大学洛杉矶分校艾滋病自然史研究是多中心艾滋病队列研究的四个中心之一。有1637名受试者入组UCLA，5622名受试者入组MACS。目前约有1800名活跃受试者入组。受试者每半年随访一次，接受MACS范围的问卷调查、一系列神经心理学测试、简短的体格检查和常规血液采集以及可能的精液、唾液、尿液或粪便样本采集。NIAID提供的补充资金用于公开招聘，以提高统计能力，招收拉丁美洲和非洲裔美国少数民族以及年轻（<39岁）的高加索男子，这些群体目前受艾滋病毒/艾滋病影响最大，目标是招收反映当前流行病的族裔群体。Harbor GCRC的受试者总入组人数估计约为240名男性，每人每年将接受两次访视。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Multicenter AIDS Cohort Study is a prospective cohort study that was begun in 1984 to follow HIV seropositive and seronegative men. The UCLA Natural History of AIDS Study is one of four centers of the Multicenter AIDS Cohort Study. There are 1637 subjects enrolled at UCLA, and 5622 MACS-wide. There are now about 1800 active subjects enrolled. Subjects are followed semi-annually who undergo administration of the MACS-wide questionnaires, a battery of neuropsychologic tests, a brief physical examination, and the routine collection of blood and possible collection of semen, saliva, urine, or stool samples. Supplemental funding from NIAID was awarded to open recruitment in order to improve statistical power and enroll Latino and African-American minorities, as well as younger (<39 yrs) Caucasian men, the groups currently most affected by HIV/AIDS, with the goal of enrolling ethnic groups reflective of the current epidemic. Total enrollment of subjects at Harbor GCRC is estimated at about 240 men who will each have two visits epr year.