BONE DENSITY IN AGING MEN OF DIVERSE RACE AND ETHNICITY

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。不同种族/民族老年男性的骨密度是由美国国立卫生研究院（NIH）资助的麦金利博士的研究《少数民族男性泌尿系统疾病流行病学》的一个子研究，该研究将由新英格兰研究所（NERI）与Michael F. Holick博士及其同事合作进行。本研究是一项基于老年男性（OSAM）人群的横断面观察性调查，研究将在中老年西班牙裔、非西班牙裔黑人和非西班牙裔白人男性的血液和尿液中测量骨矿物质密度、钙和骨代谢参数。这个项目的意义在于，骨质疏松症影响着美国100万到200万的老年男性。患有骨质疏松症的男性发生骨折和骨折相关残疾的风险增加。由于大多数骨质疏松症研究都是在女性中进行的，因此对男性，特别是西班牙裔和非裔美国人的骨质疏松症知之甚少。本研究将有助于为研究人群提供骨质疏松症的风险信息和可能的预防方法。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Bone density in aging men of diverse race/ethnicity is a sub-study of Dr. McKinlay's NIH funded study Epidemiology of Urologic Disorders in Minority Men that will be conducted by New England Research Institutes (NERI) in collaboration with Dr. Michael F. Holick and his colleagues. This study is a cross-sectional Observational Survey of Aging Men's (OSAM) population based study of bone mineral density and parameters of calcium and bone metabolism that will be measured in blood and urine in middle-aged and elderly Hispanic, non-Hispanic Black and non-Hispanic White men. The significance of this project is that osteoporosis affects between 1 and 2 million older men in the United States. Men with osteoporosis have increased risk for fractures and fracture-related disability. Because most osteoporosis research has been performed in women, much less is known about this disease in men, especially of Hispanic and African American origin. This study will help provide information about risks of osteoporosis and possible approaches for prevention in this study population.