POLY MVA UTILIZED AS NEUROPROTEIN IN CHRONIC HYPERTENSION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。一些有高血压病史的人会出现脑深部血管硬化和血流减少。这会导致氧气供应减少，进而导致能量供应减少，并可能导致脑细胞死亡。这种情况被称为“小血管疾病”(SVD)。目前还没有FDA批准的治疗这种疾病的方法。我们石溪分校一直在研究一种名为Poly-MVA的膳食补充剂作为预防小血管疾病的效果。这种补充剂起到了“能量增强剂”的作用；它有能力将能量转移到细胞中。我们相信，这可能会防止易发地区的细胞死亡。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Some people with a history of high blood pressure develop hardening and reduced flow in the deep blood vessel of the brain. This results in areas of decreased oxygen delivery, which then results in decreased energy supply and possible brain cell death. This condition is called " Small Vessel Disease" (SVD) . There is no current FDA-approved treatment for this condition. We at Stony Brook have been studying the effects of a dietary supplement , Poly-MVA, as a protection against Small Vessel Disease. This supplement acts as an "energy boost" ; it has the ability to transfer energy to cells. We believe this may prevent cell death in vunerable areas.