MULTIDETECTOR CT DIAGNOSIS OF PULMONARY EMBOLISM

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这是一项前瞻性的观察性试验，旨在评估多层计算机辅助断层扫描(CT)血管成像和CT静脉成像在静脉血栓栓塞症诊断中的阴性预测价值。CT血管造影阴性的患者将在检查后3个月内接受随访，以确定他们是否有后续静脉血栓栓塞症的证据。复发性静脉血栓栓塞症的诊断将成为诊断试验和确定试验阴性预测值的参考标准。理想情况下，这将使我们能够使用CT血管造影术和CT静脉造影术作为一步解决肺栓塞诊断问题的方法。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a prospective observational trial to assess the negative predictive value of combined multidetector computer assisted tomography (CT) angiography and CT venography in the diagnosis of venous thromboembolism. Patient's with negative CT angiograms will be followed for 3 months after testing to determine whether or not they have evidence of subsequent venous thromboembolism. The diagnosis of recurrent venous thromboembolism will be the reference standard for diagnositc testing and to determine the negative predicted value of the test. Ideally, this will allow us to use CT angiography combined with CT venography as a one-step solution to the problem of pulmonary embolism diagnosis.