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INFLUENCE OF REPETITIVE HYPOXIC APNEA ON AUTONOMIC AND CARDIOVASCULAR CONTROL

INFLUENCE OF REPETITIVE HYPOXIC APNEA ON AUTONOMIC AND CARDIOVASCULAR CONTROL
重复性缺氧呼吸暂停对自主神经和心血管控制的影响
批准号:
7378496
负责人:
KEVIN D MONAHAN
金额:
$0.77万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-04-01 至 2007-03-31

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项目成果

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中文摘要
翻译
本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者(PI)可能已经从另一个NIH来源获得了主要资金,因此可以在其他CRISP条目中表示。列出的机构是中心的,不一定是研究者的机构。该项目的目的是确定重复性缺氧呼吸暂停(RHA)对静止状态和生理应激源下自主神经和心血管调节的影响。研究人员假设RHA会损害压力反射敏感性,增加休息时和生理应激时的交感神经流出,并改变骨骼肌对生理应激的血流反应。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this project is to determine the effect of repetitive hypoxic apnea (RHA) on autonomic and cardiovascular regulation both at rest and in response to physiological stressors. The investigators hypothesize that RHA will impair baroreflex sensitivity, augment sympathetic outflow at rest and during physiological stressors, and alter skeletal muscle blood flow responses to physiological stressors.
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