PERCUTANEOUS ELECTRICAL NERVE STIMULATION FOR LOW BACK PAIN

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。这是一项经皮刺激治疗慢性腰痛的初步研究。共入组20例患有中度至重度慢性腰/骶椎疼痛的受试者。约10名受试者将被随机分配接受通过腰背部区域临时植入的导线电极输送的经皮刺激。约10名受试者将被随机分配接受通过连接到下背部区域的市售自粘电极输送的表面刺激。两组均接受每天6小时的刺激，持续6周，并随访6个月。将使用标准化测量工具评估疼痛强度/干扰、背痛特异性残疾和生活质量。将对两组的结果进行分析和比较，以估计经皮治疗相对于表面治疗的效果大小和优效性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a pilot study of percutaneous stimulation to treat chronic low back pain. A total of 20 subjects with moderate-to-severe chronic lumbar/sacral spine pain will be enrolled. Approximately 10 subjects will be randomly assigned to receive percutaneous stimulation delivered via temporary implanted wire electrodes in the low back region. Approximately 10 subjects will be randomly assigned to receive surface stimulation delivered via commercial self-adhering electrodes attached to the low back region. Both groups will receive a total of 6-hour stimulation per day for 6 weeks and will be followed up for 6 months. Pain intensity/interference, back-pain-specific disability, and quality-of-life will be assessed using standardized measurement instruments. The outcomes from the two groups will be analyzed and compared to estimate the effect size and the superiority of the percutaneous to the surface treatment.