BRIN: UPR MED SCI: SCIENTIFIC RESEARCH CORE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。Conchita Zuazaga博士是研究核心的负责人。研究核心负责监督技术转移旅行奖、获取生物医学电子科学信息计划、DNA测序和多位点基因分型设施，以及十一(11)个科学子项目。Zuazaga博士与AABRE-PR主任和EAC一起监督了NCRR支持的十一(11)个科学子项目的进展。它们是：图拉博大学1.塞萨尔·M·洛扎诺。新铂(II)配合物的合成、表征及其对核苷鸟苷的反应。2.阿纳斯塔西奥·埃米利亚诺。来自热带真菌的潜在生物活性代谢物。3.西尔维娜·菲罗西。BEP和BaP与氧和氮氧化物的反应机理：微环境的影响。波多黎各大学胡马考分校4.安东尼奥·E·阿雷格里亚。喹酮类化合物的光敏还原及其与DNA的共价结合。5.卡门·赫尔南德斯。神经系统对尖吻林蛙腭部粘液纤毛活动的影响6.加布里埃尔·巴莱塔。有机溶剂中的酶催化剂。7.Margarita Ortiz-Marciales。合成烟碱受体激动剂氨基衍生物的新方法。波多黎各大学马亚圭兹分校8.玛德琳·托雷斯-卢戈软性材料包裹蛋白质的分子研究。9.伊万·费雷尔-罗德里克斯。约氏疟原虫ABC基因的鉴定与表达分析。大都会大学10.比阿特丽斯·扎亚斯。新型苯并唑并[3，2-a]喹啉盐类抗癌药物的DNA相互作用和突变活性。11.卡伦·瓦内萨·冈萨雷斯。半乳糖血症晶状体的细胞周期变化。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dr. Conchita Zuazaga directs the Research Core. The Research Core oversees the Technology Transfer Travel Awards, the Access to Biomedical Electronic Scientific Information program, the DNA Sequencing and Multilocus Genotyping facility, and eleven (11) scientific subprojects. Together with the AABRE-PR Director and EAC, Dr. Zuazaga oversaw the progress of the eleven (11) NCRR supported scientific subproject. These are: Turabo University 1. Cesar M. Lozano. Synthesis, Characterization and Reaction Toward the Nucleoside Guanosine of New Platinum(II) Complexes. 2. Anastacio Emiliano. Potentially Bioactive Metabolites from Tropical Fungi. 3. Silvina Fioressi. Reaction Mechanisms of BeP and BaP with Oxygen and Nitrogen Oxides: the Effect of the Microenvironment. University of Puerto Rico-Humacao 4. Antonio E. Alegria. Photosensitized Reduction of Quinones and Covalent Binding to DNA. 5. Carmen Hernandez. The Influence of the Nervous System on Mucociliary Activity in the Frog Palate of Rana pipiens. 6. Gabriel Barletta. Enzyme Catalysts in Organic Solvents. 7. Margarita Ortiz-Marciales. New Methodologies for the Synthesis of Amino Derivatives as Nicotinic Receptor Agonists. University of Puerto Rico-Mayaguez 8. Madeline Torres-Lugo. Molecular Studies of Proteins Encapsulated in Soft Materials. Universidad Interamericana Bayamon 9. Ivan Ferrer-Rodriquez. Identification and expression analysis of ABC genes in Plasmodium yoelii. Universidad Metropolitana 10. Beatriz Zayas. DNA Interaction and Mutational Activity of Novel Benzazolo[3,2-a]quinolinium Salts Anticancer Drugs. 11. Karen Vanessa Gonzalez. Cell Cycle Changes in the Galactosemic Lens.