BRIN: UL: GENOMICS CORE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。路易斯维尔大学基因组学核心共享、集中的研究核心设施旨在为路易斯维尔大学及其KBRIN/INBRE附属机构提供测序和基因微阵列服务。我们继续支持布朗癌症中心Affymetrix设施的微阵列服务。该设施已经对来自12个实验室的244个芯片进行了分析。INBRE研究团队的合作正在进行中。具体地说，我们正在与莫尔黑德州立大学的韦斯利·怀特博士、西肯塔基大学的谢丽尔·戴维斯博士和北肯塔基大学的马克·巴吉特博士一起进行基因阵列杂交和分析。该小组正在考虑通过肯塔基州EPSCoR开发合作研究开发计划的应用程序。这可能提供可能导致NSF和/或NIH协作应用的试点数据。我们支持贝拉明大学的戴夫·罗宾逊博士和玛丽·赫夫博士参加路易斯维尔大学为期一周的肯塔基州蛋白质组学培训计划，以提高他们的研究技能和目标。Bellarmine今年已经收到了六份GenBank提交的材料。来自贝拉明大学的NCBI GenBank成员：Steckler，NK，JM Lau和DL Robinson。2004年。智人NCBI AY736855：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=52630904 lau JM、NK Steckler和DL Robinson中类odz3基因的鉴定2004年。在马尾猴中检测到与强直性肌营养不良相关的3‘非翻译CTG-重复区域。NCBI加入号AY640034：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4924 966刘，JM，NK Steckler和DL Robinson。2004年。从休闲鹿中分离出一个类似ODZ3的发育基因。NCBI加入号AY640033：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4924 964刘，JM，NK Steckler和DL Robinson。2004年。哺乳动物ODZ基因家族中阿萨姆猕猴发育基因的分离。NCBI登录号AY626784：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4847 041Lau，JM，TM Brittian，RB Burns和DL Robinson。2004年。哺乳动物ODZ基因家族狐猴发育基因的分离。NCBI加入号AY529203：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4279 780霍华德，JM，S·威尔特。2004年。SU scrofa claudin-3m RNA。NCBI加入号AY625258：http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4837 875。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. University of Louisville Genomics Core The shared, centralized research core facility is designed to provide sequencing and gene-micro-array services to the University of Louisville and its KBRIN/INBRE affiliated institutions. We have continued to support the micro-array services of the Affymetrix facility in the Brown Cancer Center. The facility has performed analyses on 244 chips from 12 laboratories. Collaboration is on going with INBRE research teams. Specifically we are in the midst of performing gene array hybridization and analyses for with Dr. Wesley White at Morehead State University, Dr. Cheryl Davis at Western Kentucky University, and Dr. Mark Bardgett at Northern Kentucky University. This group is considering the development of a Collaborative Research Development Program application through Kentucky EPSCoR. This might provide pilot data that could lead to a NSF and/or an NIH collaborative application. We have provided support for Drs. Dave Robinson & Mary Huff, of Bellarmine University, one of our outreach institutions, to attend the week long Kentucky Proteomics Training Program at the University of Louisville to further their research skills & aims. Bellarmine has had six GenBank submissions this year. NCBI GENBANK ACCESSIONS from Bellarmine University: Steckler, NK, JM Lau and DL Robinson. 2004. Identification of ODZ3-like gene in Homo sapiens NCBI Accession AY736855: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=52630904 Lau JM, NK Steckler and DL Robinson. 2004. Detection in vervet monkey of the 3' untranslated CTG-repeat region associated with myotonic dystrophy. NCBI Accession Number AY640034: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4924 966 Lau, JM, NK Steckler and DL Robinson. 2004. Isolation of an ODZ3-like developmental gene from fallow deer. NCBI Accession Number AY640033: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4924 964 Lau, JM, NK Steckler and DL Robinson. 2004. Isolation of a developmental gene from Assamese macaque belonging to the mammalian ODZ gene family. NCBI Accession Number AY626784: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4847 041 Lau, JM, TM Brittian, RB Burns and DL Robinson. 2004. Isolation of a developmental gene from lemur belonging to the mammalian ODZ gene family. NCBI Accession Number AY529203: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4279 780 Howard, JM, and S Wilt. 2004. Sus scrofa claudin-3 mRNA. NCBI Accession Number AY625258: http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=4837 875 .