Biomedical Simulations Resource

南加州大学的生物医学模拟资源(BMSR)于9月成立 1985至批准号RR-01861来自美国国立卫生研究院国家研究资源中心。BMSR是 致力于通过技术手段推进生物医学建模和模拟的最先进水平 研究与开发(核心)和协作研究项目。它还寻求传播这一点 通过针对生物医学的服务、培训和传播活动提供知识和相关软件 整个社区。后一项活动包括开发和分发建模/仿真软件，简称 除公开文献出版物外，还举办课程、讲习班和出版研究卷。强调…… 核心研究项目是关于高级建模和仿真方法的开发以及他们的 在生理系统中的应用，以促进知识的进步和临床实践的改进。这个 具有挑战性的非线性动态系统、稀疏数据建模、闭环生理控制和多变量案例 复杂的系统构成了这一努力的焦点。核心项目开发的方法 处于这一领域研究的前沿。他们的有效研究是由计算设施和 汇聚在BMSR中的人力资源。这些方法的关键应用包括各种 生理领域，包括药代动力学、心肺、代谢、神经和感觉系统。 作为已开发方法的试验场和传播手段的其他应用程序包括 在我们的协作项目中制造。充分开发和测试的方法以用户友好的方式实施 软件包，并向广大生物医学界提供。 BMSR的服务、培训和传播活动旨在促进知识和 生物医学建模和仿真领域的技术。他们还致力于创建一个互动的社区 调查人员，这可以提供超越障碍所需的多学科科学/技术动力 由于主题的复杂性所强加的。BMSR的最终目标是促进仿真的传输 以科技为临床环境，改善我国医疗保健体系。

The Biomedical Simulations Resources (BMSR) at the University of Southern California was established in September 1985 through Grant No. RR-01861 from the National Center for Research Resources of the NIH. The BMSR is dedicated to the advancement of the state-of-the-art in biomedical modeling and simulation through Technological Research and Development (Core) and Collaborative Research projects. It also seeks the dissemination of this knowledge and related software through Service, Training and Dissemination activities aimed at the biomedical community at large. The latter activities include development and distribution of modeling/simulation software, short courses, workshops and publication of research volumes - in addition to publications in open literature. The emphasis of the Core Research projects is on development of advanced modeling and simulation methodologies and their application to physiological systems for the advancement of knowledge and improvement of clinical practice. The challenging cases of nonlinear dynamic systems, sparse data modeling, closed-loop physiological control, and multivariate complex systems, constitute the focal points of this effort. The methodologies developed by the Core projects are at the cutting-edge of research in this area. Their effective study is made possible by the computing facilities and human resources that are brought together in the BMSR. Pivotal applications of these methodologies cover a variety of physiological domains, including pharmacokinetics, cardio-respiratory, metabolic, neural and sensory systems. Additional applications, serving as testing grounds and disseminations means for the developed methodologies, are made in our Collaborative projects. Fully developed and tested methodologies are implemented in user-friendly software packages and made available to the biomedical community at large. The Service, Training and Dissemination activities of the BMSR seek to promote the exchange of knowledge and technology in the area of biomedical modeling and simulation. They also aim at creating an interactive community of investigators, which can provide the multi-disciplinary scientific/technological impetus needed to transcend the barriers imposed by the complexity of the subject. The ultimate objective of the BMSR is to facilitate transfer of simulation science and technology to the clinical environment for the improvement of our health care system.