REGIONAL BIOCONTAINMENT LABORATORY (RBL) NEWARK CENTER

描述（由申请人提供）：一个区域生物控制实验室（RBL）被提议作为新泽西州纽瓦克国际公共卫生中心（ICPH）的扩展。ICPH是作为新泽西医学和牙科大学-新泽西医学院（NJMS）和公共卫生研究所（PHRI）之间的伙伴关系开发的；它设有PHR1I，微生物学和分子遗传学部门以及NJMS的国家结核病中心。拟议的RBL将增加4250平方英尺（GSF）的BSL-2实验室空间和13480平方英尺（GSF）的BSL-3实验室和动物空间，以容纳来自第二区域卓越区域中心（RCE）的越来越多的传染病和生物防御研究人员。ICPH目前为纽瓦克的研究人员提供了一个增强的7500平方英尺的BSL-3实验室和动物空间。它还作为第二区域RCE的主要动物核心设施，这将很快强调其能力。拟议的RBL扩展了ICPH的研究能力，同时最大化了其现有的支持基础设施。NJMS和PHRI将为RBL招募五名新的常驻生物防御研究人员。它还将为两名长期访问的RCE科学家提供设施，并为第二区RCE研究人员提供短期通勤空间。（在参与第二区域RCE计划的208名科学家中，超过50%的人在拟议的RBL 25英里范围内工作）。当RBL投入使用时，它将在纽瓦克培养大量的生物防御科学家，并作为新兴地区和国家生物防御需求的专门实验室。

DESCRIPTION (provided by applicant): A Regional Biocontainment Laboratory (RBL) is proposed as an expansion to the International Center for Public Health (ICPH) in Newark, New Jersey. The ICPH was developed as a partnership between the University of Medicine and Dentistry of New Jersey-New Jersey Medical School (NJMS) and the Public Health Research Institute (PHRI); it houses PHR1I and the Department of Microbiology and Molecular Genetics and National Tuberculosis Center of NJMS. The proposed RBL will add 4,250 gross square feet (GSF) of BSL-2 laboratory space and 13,480 GSF of BSL-3 laboratory and animal space to accommodate a growing number of infectious diseases and biodefense researchers from the Region II Regional Center of Excellence (RCE). The ICPH currently features an enhanced 7,500 GSF core of BSL-3 lab and animal space for Newark-based researchers. It also serves as a primary animal core facility for the Region II RCE, which will quickly stress its capacity. The proposed RBL expands the ICPH research capability while maximizing its pre-existing support infrastructure. Five new resident biodefense research faculty will be recruited by NJMS and PHRI for the RBL. It will also provide facilities for two long-term visiting RCE scientists and short-term space for commuting Region II RCE investigators. (Of the 208 scientists participating in the Region II RCE program, over 50% work within 25 miles of the proposed RBL). When the RBL is operational, it will create a critical mass of biodefense scientists in Newark and serve as a specialized laboratory for emerging regional and national biodefense needs.