PS06-011, HIV Prevention with HIV+ Incarcertated Men

描述（由申请人提供）：这项可行性研究将测试同伴领导的小组水平干预的有效性，主要针对非裔美国人、拉丁裔美国人和白人艾滋病毒感染者（200名男性，每种情况随机选择100名），年龄在18岁及以上。干预措施的目的是通过提倡禁欲、一夫一妻制和使用避孕套，以及增加从监狱释放后获得适当医疗和预防服务的机会，减少艾滋病毒的传播。干预措施将与PA惩戒部门的护理标准进行比较。这项拟议的研究有6个目标为指导：(1)在即将从州监狱释放（6个月内）的艾滋病毒阳性男性中，测试旨在降低艾滋病毒风险行为的干预措施与标准护理措施的效果；(2)测试干预措施对增加出狱后获得适当药物滥用治疗和预防复发服务的有效性；(3)测试干预措施对提高与伴侣咨询转介服务相关的态度和技能的影响；(4)检验增加获得保健，包括社会服务和医疗的机会的干预措施的效力；(5)测试干预的有效性，以提高干预条件下男性利用服务的能力，促进医疗依从性；(6)将干预措施的成本和收益与护理标准进行比较。参与者将获得非金钱奖励，以尽量减少人员流失，并在干预前，2周，3和6个月完成评估。措施包括：(1)艾滋病毒传播风险；(2)与性伴侣交往；(3)获得和利用药物滥用治疗；(4)获得和利用与艾滋病有关的保健和社会服务。采用多元回归和逻辑回归对目标进行统计评价。

DESCRIPTION (provided by applicant): This feasibility study will test the efficacy of a peer led group level intervention primarily targeting African American, Latino American, and White HIV+ inmates (200 men, 100 randomized per condition), age 18 and older. The intervention is designed to reduce HIV transmission by promoting abstinence, monogamy, and using condoms as well as increase access to appropriate medical treatment, and prevention services after release from prison. The intervention will be compared against the PA Dept of Corrections standard of care. The proposed study is guided by 6 aims, to: (1) Test the efficacy of an intervention designed to reduce HIV risk behavior compared to the standard of care among HIV+ men soon to be released (within 6 months) from a state prison; (2) Test the efficacy of the intervention to increase access to appropriate substance abuse treatment and relapse prevention services after release from prison; (3) Test the intervention to increase attitudes and skills related to partner counseling referral services (PCRS); (4) Test the efficacy of the intervention to increase access to care, including social services and medical treatment; (5) Test the efficacy of the intervention to increase the abilities of men in the intervention condition to utilize services to promote adherence to medical treatment; and (6) Compare the intervention's costs and benefits to the standard of care. Participants will receive non-monetary incentives to minimize attrition, and complete assessments before the intervention, at 2 weeks, 3, and 6 months post. Measures include (1) HIV transmission risks; (2) communicating with sexual partners; (3) access and utilization of substance abuse treatment, and, (4) access and utilization of AIDS-related health and social services. The aims will be evaluated statistically with multiple regression and logistic regression.