Predoctoral Training Program in Genetics

描述（由申请人提供）：耶鲁大学遗传学博士前培训项目需要持续支持。该项目涉及来自11个不同部门的57名培训师。主要的管理和培训机构是耶鲁大学文理学院的分子、细胞和发育生物学（MCDB）、生态和进化生物学（EEB），以及耶鲁大学医学院的遗传学系。目前在主要参与部门注册的研究生人数为79人（MCDB）， 53人（遗传学）和29人（EEB）。MCDB和遗传学系的学生通过生物和生物医学科学（BBS）的跨部门联合项目进入大学。大多数新学员都有生物学或生物化学学士学位。研究生入学考试成绩和平均绩点高的学员可被录取。研究成果和与受训者一起做过研究的科学家的推荐信将受到特别关注。该项目提供现代遗传学各个方面的培训，包括临床遗传学、基因组学和生物信息学、发育遗传学、免疫遗传学、癌症遗传学、进化和群体遗传学。学生有机会使用各种模式生物，包括果蝇、秀丽隐杆线虫、酵母、拟南芥、玉米、大肠杆菌、病毒和小鼠。第一年的培训包括正式的课程作业和研究轮岗。在第二年，学生继续课程学习并开始论文研究。作为第二年进行的资格考试的一部分，每个学生都应该展示对一些广泛主题领域的掌握，并准备和捍卫一个或多个研究提案。后来的几年致力于论文研究和论文的准备。所有学生接受监督教学经验。大多数毕业生继续从事博士后研究，其中许多人随后在学术和研究机构获得独立职位。此外，许多毕业生在生物技术和制药公司获得研究职位。请拨经费支助每年18名研究生，为期5年

DESCRIPTION (provided by applicant): Continuing support is requested for Yale's Predoctoral Training Program in Genetics. The program involves 57 trainers from a total of 11 different departments. The principal administrative and training entities are the Departments of Molecular, Cellular and Developmental Biology (MCDB) and Ecology and Evolutionary Biology (EEB) in the Yale University Faculty of Arts and Sciences, and the Department of Genetics in the Yale University School of Medicine. The numbers of graduate students currently enrolled in the primary participating departments are 79 (MCDB), 53 (Genetics) and 29 (EEB). Students in the Departments of MCDB and Genetics enter the university through the interdepartmental Combined Program in the Biological and Biomedical Sciences (BBS). Most incoming trainees have a Bachelor's degree in biology or biochemistry. Admission is granted to trainees whose graduate record exam scores and grade point averages are high. Particular attention is paid to research accomplishments and letters of recommendation from scientists with whom the trainee has done research. The program offers training in all aspects of modern genetics, including clinical genetics, genomics and bioinformatics, developmental genetics, immunogenetics, cancer genetics, evolutionary and population genetics. Students have the opportunity to work with a variety of model organisms, including Drosophila, C. elegans, yeast, Arabidopsis, maize, E. coli, viruses and mice. Training in the first year includes formal course work and research rotations. In the second year, students continue course work and begin thesis research. As part of the qualifying exam administered in year two, each student is expected to demonstrate mastery in a number of broad topic areas and to prepare and defend one or more research proposals. Later years are devoted to thesis research and preparation of a dissertation. All students receive supervised teaching experience. The majority of graduates go on to do postdoctoral research, and many of these subsequently obtain independent positions at academic and research institutions. In addition, many graduates obtain research positions in biotechnology and pharmaceutical companies. Funds are requested to support 18 graduate students per year for a five-year period