Pre and Post Doctoral Training: UMKC School of Dentistry

描述（由申请人提供）：本提案是对培训补助金DE07294（11至15年）的修订竞争性续期，是对美国国立牙科和颅面研究所（National Institutes of Dental and Craniofacial Research）重新发布PAR-00-116的直接回应，发布日期：2005年5月5日。该提案旨在培养一支高技能，互动的科学家骨干，他们可以成功地应对牙科，口腔和颅面研究领域不断扩大的机会。培训计划是高度跨学科的设计，服务于博士前和博士后培训水平的各种互动学科。由于培训水平的多样性，以及研究和教育项目的跨学科和转化/临床重点，导师和主任处于独特的位置，可以有效和直接地响应项目公告中概述的目标。培训计划的目标是：1)培养牙科科学家进行临床相关的口腔健康研究；2)培养多学科的口腔和颅面科学研究骨干；3)培养下一代牙科学院师资队伍。培训强调三个主要研究领域，包括：1)骨生物学；2)牙科生物材料（包括生物力学、生物信息学、牙科和颅面生物工程）；3)牙科转化/临床研究。这些培训和研究工作的增长在过去五年中大大扩大。亮点包括：1)14000平方米的建筑面积。在2004年4月完成并占用了1英尺的额外研究空间；2)外来研究资助增加三倍，由2001年的150万元增至2006年的逾500万元；3)从2001年的4个职位增加到2006年的13个职位；4)各种来源支持的学员人数从2001年的15人增加到2006年的52人。每年培训将有10至12名牙科暑期研究奖学金学生，由牙科学校基金资助；10名工科学生，为期10周的培训，由“工程师口腔科学研究培训计划”（DK 069501）资助；全日制博士预科生3名；5名牙医攻读跨学科博士学位；两名基础科学教员和/或牙科教员短期实习生。总共要求在第11年级、第12年级和第13至15年级分别任命8名、9名和10名全职博士前和博士后培训人员。为11至15年级的教员申请两个短期培训职位。该提案的一个主要组成部分是对牙医进行足够深入的科学方法培训，使他们成为合作的、跨学科的、合理独立的、基础的和/或转化的/临床的研究人员。

DESCRIPTION (provided by applicant): This proposal is a revised competing renewal of training grant, DE07294 (years 11 through 15), and is in direct response to the reissue of PAR-00-116 from the National Institutes of Dental and Craniofacial Research, release date: May 5, 2005. The proposal is designed to develop a cadre of highly skilled, interactive scientists who can successfully address the expanding opportunities in dental, oral, and craniofacial research. The training program is highly interdisciplinary by design, serving a wide variety of interactive disciplines at pre-doctoral and post-doctoral training levels. Because of the variety of training levels, and the interdisciplinary and translational/clinical emphasis in the research and educational programs, the mentors and the Director are uniquely positioned to respond effectively and directly to the goals outlined in the program announcement. The goals of the training program are to: 1) produce dentist-scientists to conduct clinically relevant oral health research; 2) train a multi-disciplinary cadre of talented investigators for careers in dental and craniofacial science; and 3) develop the next generation of dental school faculty. The training emphasizes three primary research areas which include: 1) bone biology; 2) dental biomaterials (including biomechanics, bioinformatics and dental and craniofacial bioengineering); and 3) dental translational/clinical research. The growth of these training and research efforts has greatly expanded over the past five years. Highlights include: 1) the construction of 14,000 sq. ft. of additional research space was completed and occupied in April, 2004; 2) a threefold increase in outside research funding support from $1.5M in 2001 to over $5.0M in 2006; 3) an increase in filled tenure track faculty positions from 4 in 2001 to 13 in 2006; and 4) an increase in the number of trainees supported from a variety of sources increased from15 in 2001 to 52 in 2006. For each year of training there will be 10 to 12 dental summer research fellowship students supported from dental school funds; 10 engineering students for 10 weeks of training, who will be funded from "Dental Science Research Training Program for Engineers" (DK 069501); three full-time pre-doctoral students; five dentists pursuing interdisciplinary Ph.D. degrees; and two basic science faculty and/or dental faculty short-term trainees. A total of eight full-time appointments are requested for year 11, nine in year 12 and 10 in years 13 through 15 in pre- and post-doctoral training. Two short-term training positions for faculty are requested for years 11 through 15. A main component of the proposal is to train dentists in the scientific method in sufficient depth to enable them to become collaborative, interdisciplinary, reasonably independent, basic, and/or translational/clinical researchers.