Improving Weight Loss Outcomes in African Americans

描述(由申请人提供)： 候选人：Jamy D.Ard，医学博士，积极致力于临床研究的学术生涯。他在过去已经证明了他完成项目和独立工作的能力，并通过这笔赠款提供的教育和培训展示了成为一名富有成效的研究人员所必需的素质。赞助商：W.蒂莫西·加维，医学博士，营养科学部主任，有指导临床研究人员的长期记录。阿拉巴马大学伯明翰分校(UAB)临床营养研究中心主任大卫·艾利森博士和综合临床研究中心(GCRC)实验室核心主任芭芭拉·高尔博士将担任共同发起人。杜克大学高血压中心主任Laura Svetkey博士也将作为共同发起人发挥关键作用，她将参与对Ard博士进展的正式评估，并在研究计划中提出的活动上进行合作。环境：UAB提供深度和多样性的临床研究努力，以及支持K23应用所需的最先进的物理资源。这项提案将利用的具体资源包括UAB的NIH资助的临床营养研究中心、UAB Pittman GCRC、K30临床研究培训计划，以及营养科学部内的研究设施和资源。研究：这个培训机会的建议是探索管理非裔美国人肥胖的最佳方法，结合行为和生理角度。该研究计划的具体目标包括确定非洲裔美国人减肥的文化上适当干预的关键组成部分，并表征强调水果、蔬菜、膳食纤维和低脂乳制品的饮食模式对非裔美国人心血管危险因素的生理影响。拟议中的培训和研究将为阿尔德博士提供必要的技能和经验，以推动他的职业生涯，成为非裔美国人等特殊人群中肥胖问题的独立调查员。

DESCRIPTION (provided by applicant): Candidate: Jamy D. Ard, MD, is motivated and committed to an academic career involving clinical research. He has demonstrated his ability to complete projects and work independently in the past, and shows the qualtities necessary to become a productive researcher with the education and training provided by this grant. Sponsors: W. Timothy Garvey, MD, Chairman of the Department of Nutrition Sciences, has as long track record of mentoring clinical researchers. Dr. David Allison, director of the University of Alabama at Birmingham (UAB) Clinical Nutrition Research Center, and Dr. Barbara Gower, Director of the General Clinical Research Center (GCRC) Laboratory Core, will serve as co-sponsors. Dr. Laura Svetkey, Director of the Duke Hypertension Center, will also play a pivotal role as co-sponsor by participating in formal appraisals of Dr. Ard's progress and collaborating on activities proposed in the research plan. Environment: UAB provides depth and diversity of clinical research endeavors as well as state-of-the-art physical resources necessary to support this K23 application. Specific resources that will be utilized in this proposal include UAB's NIH funded Clinical Nutrition Research Center, the UAB Pittman GCRC, the K30 Clinical Research Training Program, and research facilities and resources within the Department of Nutrition Sciences. Research: The proposal for this training opportunity is to investigate optimal ways to manage obesity in African Americans, combining behavioral and physiologic perspectives. The specific aims of the research plan include identifying key components of a culturally appropriate intervention for weight loss in African Americans and characterizing the physiologic effects of a dietary pattern that emphasizes fruits, vegetables, dietary fiber, and low-fat dairy products on cardiovascular risk factors in African Americans. The proposed training and research will provide Dr. Ard with the necessary skills and experience to advance his career to an independent investigator in obesity in special populations such as African Americans.