Clinical Core

UMassCFAR临床核心的使命是提供基础设施和服务，促进 创新的以患者为中心的艾滋病毒研究和转化型。CFAR临床核心有以下目标： 1)促进基础科学家和临床研究人员之间的互动，以患者为导向 提高我们对艾滋病毒发病机制的理解和开发新的预防或治疗方法的研究 治疗策略；2)提供必要的专业知识和服务，以促进以病人为本和 翻译研究；3)与其他CFAR核心实验室协调服务；4)支持 培训和提升艾滋病毒相关研究方面的新调查人员；以及5)提供社区 关于艾滋病毒的教育和UMassCFAR临床艾滋病毒研究。临床核心由临床 科学核心和临床免疫学核心。临床科学核心中心提供的服务支持 设计、实施和分析以患者为中心的转化性研究，目标是 精简调查员培训和方案制定。临床部提供的其他服务 科学核心包括标本的接收、处理、储存和运输；广泛的维护， 综合临床(成人和儿童)和实验室数据库；以及一个生物统计分核心，以提供 为赠款准备、数据分析和出版提供统计咨询。临床免疫学核心 提供方案、试剂和服务，以支持以患者为中心的研究和转化性研究。在……里面 此外，UMassCFAR临床核心最近与UMassFlow细胞术核心合作，以 开发生物安全3级流式细胞仪和分选设施。在下一个资助期内，临床 CORE将与CFAR调查人员和其他CFAR核心合作，提供支持以下研究的服务 提高对HIV发病机制和防治HIV-1感染策略的认识。

The UMass CFAR Clinical Core's mission is to provide the infrastructure and services that promote innovative patient-oriented and translational HIV research. The CFAR Clinical Core has the following goals: 1) To facilitate interactions between basic scientists and clinical investigators that lead to patient-oriented studies that improve our understanding of HIV pathogenesis and the development of novel prevention or treatment strategies; 2) To provide the necessary expertise and services to facilitate patient-oriented and translational research; 3) To coordinate services with other CFAR Core Laboratories; 4) To support the training and advancement of new investigators in HIV-related research; and 5) To provide community education regarding HIV and UMass CFAR Clinical HIV Research. The Clinical Core consists of a Clinical Sciences Core and a Clinical Immunology Core. The Clinical Sciences Core provides services that support the design, implementation, and analysis of patient-oriented and translational research with the goals of streamlining investigator training and protocol development. Other services provided by the Clinical Sciences Core include specimen receipt, processing, storage, and shipment; maintenance of extensive, integrated clinical (adult and pediatric) and laboratory databases; and a Bio-Statistics Sub-Core to provide statistical consultation for grant preparation, data analysis, and publications. The Clinical Immunology Core provides protocols, reagents, and services in support of patient-oriented and translational research. In addition, the UMass CFAR Clinical Core has recently partnered with the UMass Flow Cytometry Core to develop a Biosafety Level 3 Flow Cytometry and Sorting Facility. Over the next funding period, the Clinical Core will work with CFAR investigators and other CFAR Cores to provide services supporting studies that improve our understanding of HIV pathogenesis and strategies to prevent or treat HIV-1 infection.