Identification and characterisation of novel FLT3-ITD co-operating mutations
Identification and characterisation of novel FLT3-ITD co-operating mutations
批准号:
nhmrc : 1047129
负责人:
A/Pr Ian Lewis
金额:
$43.96万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
急性髓性白血病是一种血液和骨髓的癌症。我们已经确定了在髓系疾病中与已知致癌基因FLT3-ITD一起作用的新基因。我们将详细研究这些新基因如何促进AML的发展。这将有助于开发针对具有这些突变的AML患者群体的新疗法。
英文摘要
Acute myeloid leukaemia is a cancer of the blood and bone marrow. We have identified new genes that act with the known oncogene FLT3-ITD in myeloid disease. We will examine in detail how these new genes contribute to the development of AML. This will aid in the development of new therapies for groups of AML patients with these mutations.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mab immunotherapies for myeloid leukemia patients with germline or somatic RUNX1 mutations.
-
批准号:nhmrc : GNT1145278
-
项目类别:Project Grants
-
资助金额:$76.7万
-
财政年份:2018
-
负责人:A/Pr Ian Lewis
-
依托单位:
Mab immunotherapies for myeloid leukemia patients with germline or somatic RUNX1 mutations.
-
批准号:nhmrc : 1145278
-
项目类别:Project Grants
-
资助金额:$51.86万
-
财政年份:2018
-
负责人:A/Pr Ian Lewis
-
依托单位:
FANC gene mutations in Acute Myeloid Leukaemia biology and treatment
-
批准号:nhmrc : 1145391
-
项目类别:Project Grants
-
资助金额:$60.9万
-
财政年份:2018
-
负责人:A/Pr Ian Lewis
-
依托单位:
FANC gene mutations in Acute Myeloid Leukaemia biology and treatment
-
批准号:nhmrc : GNT1145391
-
项目类别:Project Grants
-
资助金额:$90.08万
-
财政年份:2018
-
负责人:A/Pr Ian Lewis
-
依托单位:
Co-operation between GATA2 mutation or expression and RAS signalling in AML
-
批准号:nhmrc : 1086302
-
项目类别:Project Grants
-
资助金额:$57.38万
-
财政年份:2015
-
负责人:A/Pr Ian Lewis
-
依托单位:
Dissecting the role of the IL-3 receptor alpha subunit and beta-catenin in Acute Myeloid Leukaemia
-
批准号:nhmrc : 626947
-
项目类别:NHMRC Project Grants
-
资助金额:$38.9万
-
财政年份:2010
-
负责人:A/Pr Ian Lewis
-
依托单位:
Klf5 function in normal and leukaemic haemopoiesis
-
批准号:nhmrc : 626946
-
项目类别:NHMRC Project Grants
-
资助金额:$40.67万
-
财政年份:2010
-
负责人:A/Pr Ian Lewis
-
依托单位:
海外基金