CORE--PHYSIOLOGY

能量消耗的评估已经成为研究瘦小鼠和肥胖小鼠不可或缺的工具。能够进行此类评估的系统在商业上是可用的，并且可以监控 活动、氧气消耗、二氧化碳产生、喂养和饮用。从这个数据中呼吸 可以计算出商、RER和产热。然而，这些系统价格昂贵，而且 很老练。BIDMC的内分泌部有一个由外部资金购买的16个动物监测系统。为了使PPG调查人员能够使用这项技术，监测被作为一项核心服务提供。以下监测数据以Excel电子表格和图表的形式提供给提出请求的调查员，实时绘制感兴趣的变量。核心辅助实验设计和数据分析。核心的另一项服务是协助对PPG项目进行DEXA监测。

Evaluation of energy expenditure has become an indispensable tool for studies involving lean and obese mice. Systems capable of such evaluation are commercially available and can monitor activity, oxygen consumption, CO2 production, feeding and drinking. From this data respiratory quotient, RER and heat produced can be calculated. However the systems are expensive and sophisticated. The Endocrine Division at BIDMC has a sixteen animal monitoring system purchased by outside funds. To make the technology available to PPG investigators, monitoring is offered as a core service. Following monitoring data is provided to the requesting investigator as Excel spreadsheets and graphs plotting the variable of interest in real time. The core assists in experimental design and data analysis. An additional service of the core is assistance with DEXA monitoring for PPG projects.