CLINICAL TRIAL: EXENATIDE AND BODY WEIGHT IN OBESE NON-DIABETIC WOMEN

临床试验：艾塞那肽与肥胖非糖尿病女性的体重

• 批准号: 7718935
• 负责人: ELEFTHERIA MARATOS-FLIER
• 金额: $ 1.52万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7718935
• 关键词: Body Weight; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Cross-Over Studies; Diabetes Mellitus; Double-Blind Method; Energy Metabolism; Funding; Grant; Institution; Metabolic; Obesity; Placebos; Randomized; Research; Research Personnel; Resources; Satiation; Sleep; Source; United States National Institutes of Health; Week; Weight; Woman; blood glucose regulation; exenatide; non-diabetic; treatment duration

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will examine the effect of exenatide on weight, energy expenditure, satiety, sleep and metabolic parameters in moderately obese women with normal glucose homeostasis or with impaired glucose homeostasis but not frank diabetes mellitus. This is a randomized, double blind, crossover study in which subjects will receive exenatide or placebo for 16 weeks with a 2-week washout period between treatment periods.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究将检查艾塞那肽对血糖稳态正常或血糖稳态受损但未患糖尿病的中度肥胖女性的体重、能量消耗、饱腹感、睡眠和代谢参数的影响。这是一项随机、双盲、交叉研究，受试者将接受艾塞那肽或安慰剂治疗16周，治疗期之间有2周的洗脱期。