GENE-TARGETTED SNP DISCOVERY IN RHESUS MACAQUES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本项目旨在通过对20只中国恒河猴、印度恒河猴和4只食蟹猴的3‘非编码区进行测序，确定10,000个基因区域的单核苷酸多态(SNPs)。将对汇编的SNP数据进行分析，以确定印度和中国人群的等位基因频率，并确定与食蟹猴共有的和新的等位基因。结果将在公共数据库DBSNP和MonkeySNP中报告。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project aims to identify single nucleotide polymorphisms (SNPs) in 10,000 gene regions, by sequencing the 3' UTR of 20 unrelated Chinese and Indian rhesus macaques and 4 cynomolgus macaques. The compiled SNP data will be analyzed to identify allele frequencies in both Indian and Chinese populations and to identify shared and novel alleles with cynomolgus macaques. The results will be reported in the public databases dbSNP and MonkeySNP.